Results 171 to 180 of about 38,785 (280)

Maternal Perinatal Gut Microbiome Is Shaped by Traditional Farming Lifestyle and Associated With Early Childhood Atopic Disease

Allergy, EarlyView.
We assessed whether the maternal perinatal gut microbiome and serum SCFA and cord blood SCFA differ between traditional farming and urban dyads. Women following a farming lifestyle had increased microbial diversity, several differentially abundant bacterial species and functional pathways, and increased circulating SCFA. Overall maternal gut microbiome
Erin C. Davis, Courtney M. Jackson, Nichole S. Diaz, Jazmine Susana, Ashley Nelson, Richard Insel, Antti E. Seppo, Kirsi M. Järvinen   +7 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

A titanium redox-switch enables reversible C-C bond forming and splitting reactions. [PDF]

Chem Sci
G Jafari M, Fehn D, Sandoval-Pauker C, Gau MR, Meyer K, Pinter B, Mindiola DJ, Reinholdt A.   +7 more
europepmc   +1 more source

Aptamer‐mediated outer membrane destabilization overcomes low permeability resistance in Pseudomonas aeruginosa

The FEBS Journal, EarlyView.
DNA aptamers, Apt 60 and Apt 173, target the BamA protein to compromise outer membrane integrity in Pseudomonas aeruginosa, making it susceptible to Azithromycin, an antibiotic that is otherwise poorly effective due to the low‐permeability membrane.
Rupany Selvam, Michelle Khai Khun Yap, Rafael Giacomazzi, Sérgio F. Sousa, Hock Siew Tan   +4 more
wiley   +1 more source

Stabilization of the [C₂N₅]^7- Anion in Recoverable High-Pressure Eu₄Fe_0.864(6)(C₂N₅)₂ Pyronitridocarbonate. [PDF]

J Am Chem Soc
Akbar FI, Jena N, Tobeck C, Jurzick PL, Flosbach NT, Cerantola V, Bykova E, Brüning L, Aslandukov A, Spahr D, Kovalev V, Garbarino G, Pakhomova A, Aprilis G, Giordano N, Dubrovinsky L, Wickleder MS, Ruschewitz U, Abrikosov IA, Bykov M.   +19 more
europepmc   +1 more source

Inhibition of P‐glycoprotein using photoimmunotherapy in peritoneal metastasis mouse model

Photochemistry and Photobiology, EarlyView.
Photoimmunotherapy (PIT) using photoimmunoconjugates (PICs) can inhibit the function of the ATP‐binding cassette (ABC) transporter P‐glycoprotein (P‐gp) in a mouse model of peritoneal carcinomatosis. Sterile‐filtered PIC was administered in vivo via intraperitoneal (IP) injection 20 days after IP tumor cell implantation of P‐gp‐overexpressing NCI/ADR ...
Kaitlyn A. Moore, Brian Schnoor, Kathryn L. McNaughton, Idrisa Rahman, Benjamin D. Powers, Dana M. Roque, Huang‐Chiao Huang   +6 more
wiley   +1 more source

Folate-Functionalized Albumin-Containing Systems: Non-Covalent vs. Covalent Binding of Folic Acid. [PDF]

Pharmaceutics
Gorobets MG, Toroptseva AV, Abdullina MI, Khachatryan DS, Bychkova AV.   +4 more
europepmc   +1 more source

Valorization of Yacon (Smallanthus sonchifolius) peel for peroxidase production and its immobilization on alginate beads for 2,4‐dichlorophenol bioconversion

The Canadian Journal of Chemical Engineering, Volume 104, Issue 8, Page 3984-3995, August 2026.
Sodium alginate was modified with EDC/NHS for the immobilization of Yacon peel peroxidase, resulting in a novel biocatalyst for the oxidation of 2,4‐dichlorophenol. Abstract Yacon (Smallanthus sonchifolius) roots are emerging as an alternative source of peroxidase. This study aimed to extract, immobilize, and characterize the peroxidase from Yacon peel,
Mariana Gomes Oliveira, Marcela Pires Spaolonzi, Carla Ivane Ganz Vogel, Aniela Pinto Kempka, Everton Skoronski   +4 more
wiley   +1 more source

Methods for Conjugating Antibodies with Quantum Dots. [PDF]

Molecules
Sokolov P, Knysh A, Kriukova I, Samokhvalov P, Kistenev YV.   +4 more
europepmc   +1 more source

Dioxomolybdenum(VI) Complexes Supported by Fluxional Bis(amide)‐Functionalized Aminophenolate Ligands

European Journal of Inorganic Chemistry, Volume 29, Issue 22, 1 August 2026.
New bis(amide) aminophenolate ligands form dioxomolybdenum(vi) and dioxotungsten(vi) complexes showing solvent‐dependent nuclearity. Whilst monomeric complexes featuring methoxide ligands are obtained in methanol, water triggers formation of μ‐oxo‐bridged dimers via oxo exchange, verified by 18O labelling.
Pasi Vikberg, Anssi Peuronen, Manu Lahtinen, Ari Lehtonen   +3 more
wiley   +1 more source