Results 151 to 160 of about 38,785 (280)

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

Small, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom, Jae Hun Ahn, Jung Yung Kim, Kyo Chul Lee, Yong Jin Lee, Sanoj Rejinold N, Jin‐Ho Choy   +6 more
wiley   +1 more source

Thermosensitive Nanostructured Coacervates Developed by Mixing ABA‐ and AB‐Block Copolymers and Their Unique Sustained Release of Nano‐Micelles in a Regulated Manner

Small, EarlyView.
Polyion complex micelles composed of blends of ABA and AB block copolymers can form coacervates with a hexagonally packed cylinder nanostructure after heating. The resulting coacervates can release the micelles under physiological conditions in a zero‐order kinetics, possessing cargo proteins.
Takumi Egashira, Hiroshi Kamizawa, Yujiro Hamada, Wataru Fushimoto, Hiroshi Y. Yoshikawa, Yuji Higaki, Atsushi Takahara, Takeshi Mori, Yoshiki Katayama, Akihiro Kishimura   +9 more
wiley   +1 more source

Computational study of the mechanism and selectivity of [3 + 2] cycloaddition reactions between nitrone and carbodiimide leading to the formation of anticancer 1,2,4-oxadiazolidine compounds from a MEDT perspective. [PDF]

Sci Rep
Mellaoui MD, Moussaoui M, Baammi S, Jmiai A, Benhida R, Issami SE, Zejli H, Daoud R.   +7 more
europepmc   +1 more source

Osmotic Remodeling of Extracellular Vesicles for Precision Nanomedicine

Small, EarlyView.
Hypotonic lysis in bidistilled water is used to remodel B lymphocyte–derived extracellular vesicles into cargo‐depleted, structurally preserved nanovesicles. The process reduces intraluminal proteins and nucleic acids, reshapes membrane composition, and enhances tumor‐cell uptake in vitro, while allowing proof‐of‐concept reloading with exogenous agents,
Francesca Susa, Lorenzo Arnaboldi, Veronica De Giorgis, Marco Ghirimoldi, Elettra Barberis, Marco Brucale, Francesco Valle, Mario Malerba, Marta Vallino, Angelo Musicò, Roberto Frigerio, Alessandro Gori, Vera Mugoni, Claudia Voena, Roberto Pisano, Fabrizio Pirri, Silvia Arpicco, Marcello Manfredi, Tania Limongi   +18 more
wiley   +1 more source

Ultrasensitive MicroRNA Detection Combining Reduced Graphene Oxide Electrolyte‐Gated Transistors and Machine Learning

Small, EarlyView.
We developed an ultrasensitive and highly selective biosensor by integrating bio‐functionalized reduced graphene oxide (rGO) electrolyte‐gated transistors (EGTs) and machine learning (ML) to detect miRNAs (miR‐34a, miR‐34b, and miR‐34c) associated with cancer and neurological disorders.
Ana Vitória Ferreira Deleigo, Gabrielle Coelho Lelis, Maria Luisa Braunger, Stefano Casalini, Yasmin Watanabe, Gabriel Ravanhani Schleder, Wilson Tiago Fonseca, Rafael Furlan de Oliveira   +7 more
wiley   +1 more source

Comprehensive Reinvestigation of Carbodiimide Guanylation: HCl-Initiated Access to Tri- and Tetrasubstituted Guanidines. [PDF]

ACS Omega
Vlk L, Pauk K, Samsonov MA, Růžičková Z, Chlupatý T, Růžička A.   +5 more
europepmc   +1 more source

Design of Well‐Defined Meso‐ or Macroporous Carbon Nitride with an Amorphous Framework via Perovskite Fluoride Templating

Small, EarlyView.
ABSTRACT Here, we report a synthetic strategy for meso‐ or macroporous carbon nitride (C3N4) using perovskite‐type metal fluorides (KMF3, M = Co, Ni) as hard templates. The synthesis involves a two‐step thermal treatment. An initial low‐temperature polycondensation of melamine generates polymeric intermediates that stabilize the template/precursor ...
Kazuya Kozumi, Yusuke Asakura, Yusuke Yamauchi   +2 more
wiley   +1 more source

Synthesis and characterization of bifunctional nanoprobes for targeted photodynamic therapy in breast cancer treatment. [PDF]

Discov Nano
Marmo VLM, Gonçalves GC, Santos DML, Ambrósio JAR, Simioni AR, Raniero L.   +5 more
europepmc   +1 more source

Porous Organic Polymers: From Molecular Design to Scalable Technologies

Small, EarlyView.
This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem, Hadi Shayesteh, Simindokht Zarei‐Shokat, Rokhsareh Bakhtiari, Sheyda Abedi‐Banaei, Zahra Sheikhlouiharzand, Parnia Mohebimanesh, Seyed Mohammad Amin Ojagh, Bahareh Bakhtiari, Ali Maleki, Theo G. M. van de Ven, Sohrab Zendehboudi, Ali Elkamel   +12 more
wiley   +1 more source

Sustainable Fragment Peptide Synthesis (SFPS): Leveraging Oxyma as a Dual Resin Cleavage-Peptide Coupling Agent. [PDF]

ACS Omega
Pawlas J.
europepmc   +1 more source