Results 81 to 90 of about 5,486 (323)

Carbosilane Dendrimeric Carbodiimides: Site Isolation as a Lactamization Tool

, 2006
The convergent syntheses of three generations of carbosilane dendrimeric carbodiimides are described. The wedge-type building blocks were synthesized in a divergent way, starting from allyl chloride and a repetitive sequence of hydrosilylation with ...
van Maarseeen, JH, Hiemstra, Henk,, Amore, A, van Esch, J., Zeep, N, Maarseveen, Jan H. van,, van Heerbeek, R., Zeep, Niek,, Reek, Joost N.H.,, Amore, Alessia,, van Maarseveen, J.H., van Heerbeek, R, Reek, J.N.H., Reek, Joost N.H., Heerbeek, Rieko van,, Esch, Jan van,, Amore, A., Maarseveen, Jan H. van, Zeep, N., Hiemstra, H., Reek, JNH, van Esch, J   +21 more
core   +1 more source

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

Advanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang, Xiong Xie, Huidi Fan, Botao Wu, An Wang, Wenhao Dai, Zezhong Liu, Jian Li, Huoyan Tong, Jianan Li, Yujie Ren, Jinlin Wang, Xi Zhou, Hong Liu   +13 more
wiley   +1 more source

Dual Physiological Barriers Bypassed by a Silk‐Based Supramolecular Protein Delivery Platform for Neuroinflammation Mitigation in Alzheimer's Disease

Advanced Science, EarlyView.
A supramolecular nanocomplex based on phenolic‐modified silk sericin is developed to deliver antioxidant enzymes across the blood–brain barrier and escape lysosomal degradation. This dual‐barrier‐crossing system reduces neuroinflammation and improves cognitive performance in Alzheimer's disease mouse model, offering a promising strategy for protein ...
Doudou Hu, Tiandong Li, Jian He, Yujian Jiang, Yeyuan Wang, Jingchen Sun   +5 more
wiley   +1 more source

Hydricity-Promoted [1,5]-H Shifts in Acetalic Ketenimines and Carbodiimides

, 2016
2-Monosubstituted 1,3-dioxolanes and dithiolanes act as hydride-releasing fragments, transferring intramolecularly their acetalic H atom to the central carbon of ketenimine functions.
María-Mar Ortín (2518768), Ángel Vidal (2460322), Baltasar Bonillo (1354185), Mateo Alajarín (2456926), Pilar Sánchez-Andrada (2456932)   +4 more
core   +1 more source

Laser‐Induced Periodic Phase‐Transition of 2D‐MoTe2 Nanograting Template for Frequency‐Shift Digital‐SERS Immunoassay of Autoimmune Disease

Advanced Science, EarlyView.
A protocol of fs‐laser‐induced periodic phase‐transition of 2D‐MoTe2 template, inducing AuNPs@1T’‐MoTe2 nanograting, is developed. The labeled AuNPs@1T’‐MoTe2 substrate conjugated with specialized immunoglobulin G demonstrates an unexpectedly high discrimination accuracy close to unity for serological diagnosis of rheumatoid arthritis by frequency ...
Yao Yao, Lulu Cao, Xiaolin Sun, Qiang Wang, Zhiyang Xu, Tianrui Zhai, Yan Zhao, Yijian Jiang, Zhanguo Li, Yinzhou Yan   +9 more
wiley   +1 more source

Slowing Down Water: Enhanced and Cation‐responsive MRI Contrast

Angewandte Chemie, EarlyView.
The controlled modification of mesoporous silica nanoparticle side walls with kosmotropic motifs supports an ability to reduce water diffusive mobility and dramatically increase MRI contrast to levels unprecedented for highly kinetically stable Gd‐DOTA configurations (both q = 1 and q = 0).
Connor M. Ellis, James P. Smith, Matthew F. Allen, Ferenc E. Mózes, Stephen Faulkner, Jason J. Davis   +5 more
wiley   +2 more sources

Titanium-Catalyzed Hydrohydrazination of Carbodiimides

, 2016
Hydrazinediido complexes of the type [Cp*Ti­(NxylN)­(NNR2)­(L)] (R = Ph, Me; Ar, fluorene, L = tBuNH2, Py; 3a–e) have been synthesized and used as catalysts for the hydrohydrazination of a series of carbodiimides, yielding aminoguanidines or ...
Hubert Wadepohl (1264056), Peter D. Schweizer (1821775), Lutz H. Gade (1353462)   +2 more
core   +2 more sources

Conformational change of turkey‐gizzard caldesmon induced by specific chemical modification with carbodiimide [PDF]

, 1991
François Martin, Marie-Cécile Harricane, Etienne Audemard, Françoise Pons, Dominique Mornet   +4 more
openalex   +1 more source

Reactions of Lithium Amidinates or Guanidinates Toward Carbodiimides: Synthesis and Characterization of Multi-Site Triazapentadienyllithium Compounds

, 2023
Meisu Zhou, Wu Le, Hongbo Tong
openalex   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source