Results 241 to 250 of about 219,419 (292)

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

Complete genome and functional insights into Microbacterium sp. strain FBCC-B4120, a novel freshwater isolate with diverse biotechnological traits. [PDF]

PLoS One
Kim J, Kim H, Goh J, Jin CZ, Lee HG, Lee CS, Park S, Chung EJ, Park Y, Shin S, Han Y, Kwak W.   +11 more
europepmc   +1 more source

Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A

Angewandte Chemie, EarlyView.
Genetic de‐regulation of a silent biosynthetic pathway allowed isolation and characterisation of a novel glycopeptide antibiotic named biffamycin A, which harbours unprecedented 5‐chloro‐4‐methoxy tryptophan and 3R‐hydroxy(α‐D‐mannoysl)‐D‐lysine moieties and is bioactive against MRSA and VRSA.
Michael W. Brigham, Edward S. Hems, Daniel C. L. Van, Justin E. Clarke, Sergey Nepogodiev, Julius S. P. Adamson, Christian Bassi, Michael E. Webb, Glyn R. Hemsworth, Orde Q. Munro, Barrie Wilkinson, Ryan F. Seipke   +11 more
wiley   +1 more source

Comparative toxicity and biochemical impacts of certain recommended insecticides against Spodoptera littoralis (Lepidoptera: Noctuidae). [PDF]

Sci Rep
El-Morshedy AE, Shalaby AAM, Al-Shannaf HMH, Mahmoud MG, Ibrahim HAM, Hendawi MY.   +5 more
europepmc   +1 more source

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

Angewandte Chemie, EarlyView.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu, Xuehan Li, Yu Gao, Shijia Tao, Xiaofei Li, Lemei Zhao, Wenshuai Han, Hao Fan, Ying Qiu, Man Wang, Luying Zhou, Xiaoyan Fang, Wenhua Yang, Haiyang Zhang, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang, Xiangzhao Mao   +18 more
wiley   +1 more source

Molecular Basis for the Divergent Inhibition of α-Amylase and α-Glucosidase by Phenolic Acids: The Critical Role of Hydroxyl Substitution. [PDF]

Foods
Yang S, Li Y, Han W, Cao W, Hu Z, Zhu Z, Li M, Feng J, Zhang J.   +8 more
europepmc   +1 more source

Chalcone-sulfonate ester derivatives as dual urease and α-amylase inhibitors: synthesis, biological evaluation and integrated computational studies. [PDF]

RSC Adv
Noreen Z, Sadiq A, Naeem N, Raza U, Ahmed I, Al Nami SY, Hossan A, Zaki MEA, Mughal EU.   +8 more
europepmc   +1 more source

Recent advances in biomass deconstruction, microbial conversion, artificial intelligence, and carbon capture for sustainable bioenergy. [PDF]

Bioresour Bioprocess
Kumar V, Mishra S, Joshi P, Misra J, Yegneswaran PP, Mallikarjun B, Yazdani SS, Lal PB.   +7 more
europepmc   +1 more source

A three-dimensional and multivariate statistical analysis of serine-hydrolases active sites.

, 2012
EBERT, CYNTHIA, FOSCATO, MARCO, GARDOSSI, Lucia, FERRARIO, VALERIO   +3 more
core  

bifidoAnnotator: fine-grained annotation of bifidobacterial glycoside hydrolases for human milk glycan utilization. [PDF]

Microb Genom
Pucci N, Mende DR.
europepmc   +1 more source