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The Preservation of Muscle Mitochondrial Machinery During Hypometabolic Hibernation in Scandinavian Brown Bears (Ursus arctos). [PDF]
Bergouignan A +13 more
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Functional Analysis of Amino Acid Residues Responsible for Substrate Specificity of GH13_17 α‑Glucosidase from <i>Aedes aegypti</i> Saliva (AaMalI). [PDF]
Auiewiriyanukul W +4 more
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Unusual molecular architecture of a human gut microbiota β-mannanase reveals a new CBM family
Łoś N +7 more
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Carbohydrate-active enzymes (CAZymes) in the gut microbiome
Nature Reviews Microbiology, 2022The 1013-1014 microorganisms present in the human gut (collectively known as the human gut microbiota) dedicate substantial percentages of their genomes to the degradation and uptake of carbohydrates, indicating the importance of this class of molecules.
Jacob F. Wardman +3 more
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Enzyme promiscuity of carbohydrate active enzymes and their applications in biocatalysis
Current Opinion in Structural Biology, 2020The application of biocatalysis for the synthesis of glycans and glycoconjugates is a well-established and successful strategy, both for small and large scale synthesis. Compared to chemical synthesis, is has the advantage of high selectivity, but biocatalysis had been largely limited to natural glycans both in terms of reactivity and substrates.
Edward, Pallister +2 more
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Building mutational bridges between carbohydrate-active enzymes
Current Opinion in Biotechnology, 2022The commercial value of specialty carbohydrates and glycosylated compounds has sparked considerable interest in the synthetic potential of carbohydrate-active enzymes (CAZymes). Protein engineering methods have proven to be highly successful in expanding the range of glycosylation reactions that these enzymes can perform efficiently and cost ...
Jorick, Franceus +2 more
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Role of carbohydrate-active enzymes in mycorrhizal symbioses
Essays in Biochemistry, 2023Abstract Mycorrhizal fungi form mutually beneficial interactions with a wide range of terrestrial plants. During this symbiosis, the associated fungus provides mineral nutrients, such as phosphorus and nitrogen, to its host plant in exchange of photosynthesis-derived carbohydrates.
Gong, Yuhua +3 more
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Carbohydrate-active enzymes: sequences, shapes, contortions and cells
Biochemical Society Transactions, 2016The enzyme-catalysed degradation of oligo and polysaccharides is of considerable interest in many fields ranging from the fundamental–understanding the intrinsic chemical beauty–through to the applied, including diverse practical applications in medicine and biotechnology.
Gideon J, Davies, Spencer J, Williams
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