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Synthetic Strategies for FRET-Enabled Carbohydrate Active Enzyme Probes
2021Carbohydrates are an essential class of biomolecule and carbohydrate active enzymes (CAZys) catalyze their synthesis, refinement, and degradation, hence contributing an overall regulatory capacity to their underpinning physiological roles. Here we survey recent accomplishments for accessing defined carbohydrate structures, suitably equipped with FRET ...
Singh, Meenakshi +3 more
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Electrostatic studies of carbohydrate active enzymes
1995Abstract Most charged or titratable residues reside on the protein surface. Each of such residues will exhibit a titration behaviour that is dependent on the local context around the residue. As a consequence both pH, salt and docking of a ligand into the binding cavity of a protein can be expected to alter the protein electrostatics.
Antonio Baptista +5 more
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Exploring the sheep rumen microbiome for carbohydrate-active enzymes
Antonie van Leeuwenhoek, 2015The rumen is a complex ecosystem enriched for microorganisms able to degrade biomass during the animal's digestion process. The recovery of new enzymes from naturally evolved biomass-degrading microbial communities is a promising strategy to overcome the inefficient enzymatic plant destruction in industrial production of biofuels. In this context, this
Lucas Dantas, Lopes +8 more
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Functional Annotation of Fibrobacter succinogenes S85 Carbohydrate Active Enzymes
Applied Biochemistry and Biotechnology, 2010Fibrobacter succinogenes is a cellulolytic bacterium that degrades plant cell wall biomass in ruminant animals and is among the most rapidly fibrolytic of all mesophilic bacteria. The complete genome sequence of Fisuc was completed by the DOE Joint Genome Institute in late 2009.
Phillip, Brumm +7 more
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Cazypedia : carbohydrate-active enzymes, an introduction
2011CAZypedia is an online, community-driven effort to assemble a comprehensive encyclopedia of the enzymes and binding proteins involved in the synthesis and degradation of complex carbohydrates. An evolving encyclopedia of carbohydrate-active enzymes – ”CAZymes” CAZypedia is inspired by, and closely connected with, the actively curated CAZy Database (www.
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Carbohydrate-active enzyme annotation in microbiomes using dbCAN
AbstractCAZymes or carbohydrate-active enzymes are critically important for human gut health, lignocellulose degradation, global carbon recycling, soil health, and plant disease. We developed dbCAN as a web server in 2012 and actively maintain it for automated CAZyme annotation.Jinfang, Zheng +6 more
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CAZyme3D: a database of 3D structures for carbohydrate-active enzymes
Journal of Molecular BiologyAbstractCAZymes (CarbohydrateActive EnZymes) degrade, synthesize, and modify all complex carbohydrates on Earth. CAZymes are extremely important to research in human health, nutrition, gut microbiome, bioenergy, plant disease, and global carbon recycling. Current CAZyme annotation tools are all based on sequence similarity.
N R Siva, Shanmugam, Yanbin, Yin
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Strategies Shaping the Transcription of Carbohydrate-Active Enzyme Genes in Aspergillus nidulans
Journal of Fungi (Basel, Switzerland), 2022Barnabás Cs Gila +2 more
exaly
CARBOHYDRATE-ACTIVE ENZYMES IN MICROBIOMES
New Chemistry and New Opportunities from the Expanding Protein Universe, 2014openaire +1 more source