Results 131 to 140 of about 856,070 (259)

Etherification of Bio‐Based Furanic Compounds via Continuous Flow

Advanced Sustainable Systems, EarlyView.
A comprehensive investigation on the etherification of bio‐based furanic compounds using a continuous flow apparatus. Reaction conditions are optimized for the synthesis of BEMF and then used to obtain a library of BAMFs. Additionally, the self‐etherification of HMF to produce OBMF is explored both in heterogeneous and by employing the homogeneous ...
Davide Dalla Torre, Giacomo Trapasso, Nathan Jourdainne, Nathanael Guigo, Fabio Aricò   +4 more
wiley   +1 more source

Study protocol: The effect of a low-carbohydrate enteral nutrition formula on postoperative hyperglycemia in non-diabetic patients with esophageal cancer: A randomized exploratory phase II trial (ENLICHE study). [PDF]

PLoS One
Terayama M, Imamura Y, Kitazawa T, Miyazaki N, Ishii M, Takagi K, Kuriyama K, Takahashi N, Tamura M, Okamura A, Kanamori J, Watanabe M.   +11 more
europepmc   +1 more source

On the Relentless Pursuit of an Oral Insulin Delivery System: How Far is Too Far?

Advanced Therapeutics, EarlyView.
Injectable insulin preparations have far outpaced oral ones by virtue of adequate bioavailability and are driven by innovations, including insulin pumps, real‐time blood glucose monitoring, and artificial intelligence. In contrast, oral insulin delivery systems, including nanomedicines, continue to struggle and lag due to varied reasons.
Sourav Bhattacharjee
wiley   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice

Advanced Science, EarlyView.
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang, Dajun Li, Xiao Ying Li, Weizhao Lu, Huini Ding, Chengyan Qi, Xuan Wang, Jing Shen, Yafei Chi, Tiantian Li, Michelle M. Dunk, Yu An, Hongmei Huang, Kang Yu, Weili Xu, Rong Xiao, Yuandi Xi   +16 more
wiley   +1 more source

High protein intake causes gene-length-dependent transcriptional decline, shortens lifespan and accelerates ageing in progeroid DNA repair-deficient mice. [PDF]

NPJ Metab Health Dis
van Galen I, Birkisdóttir MB, Ozinga RA, Brandt RMC, Barnhoorn S, Imholz S, van Oostrom CT, van der Marel RWGN, Smit K, Rijksen YMA, Reiling E, van Steeg H, Hoeijmakers JHJ, Dollé MET, Vermeij WP.   +14 more
europepmc   +1 more source

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

Advanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai   +12 more
wiley   +1 more source

Maternal and umbilical cord plasma purine concentrations after oral carbohydrate loading prior to elective Cesarean delivery under spinal anesthesia: a randomized controlled trial. [PDF]

BMC Pregnancy Childbirth
Kotfis K, Jamioł-Milc D, Wojciechowska A, Szylińska A, Drozd A, Zimny M, Dołęgowska B, Kwiatkowski S, Dziedziejko V, Safranow K.   +9 more
europepmc   +1 more source

Programmable NIR Responsive Nanocomposite Enables Noninvasive Intratympanic Delivery of Dexamethasone to Reverse Cisplatin Induced Hearing Loss

Advanced Science, EarlyView.
In this study, saponin‐coated silica@gold nanocarriers responsive to NIR radiation is developed to enhance intratympanic drug delivery for cisplatin‐induced hearing loss (CIHL) treatment. The biocompatibility and oto‐protective properties are validated both in vitro and in vivo.
Rawand A. Mustafa, Jiali Wang, Mengzhao Xun, Jessica M. Rosenholm, Wuqing Wang, Yilai Shu, Hongbo Zhang   +6 more
wiley   +1 more source

Carbohydrates and protein [PDF]

Proceedings of the Nutrition Society, 1964
openaire   +2 more sources