Results 21 to 30 of about 554,555 (268)

Cell surface glycan engineering reveals that matriglycan alone can recapitulate dystroglycan binding and function

open access: yesNature Communications, 2022
Matriglycan, a repeating disaccharide on α-dystroglycan, is the receptor for Lassa virus and specific extracellular matrix proteins. Here, the authors demonstrate that matriglycan, in a length-dependent tunable manner, is both necessary and sufficient ...
M. Osman Sheikh   +11 more
doaj   +1 more source

Serum N-Glycome Diversity in Teleost and Chondrostrean Fishes

open access: yesFrontiers in Molecular Biosciences, 2021
Recent advances in carbohydrate chemistry, chemical biology, and mass spectrometric techniques have opened the door to rapid progress in uncovering the function and diversity of glycan structures associated with human health and disease. These strategies
Kazuhiro Aoki   +6 more
doaj   +1 more source

Application of NIR analysis to verify cocoa powder authenticity

open access: yesCzech Journal of Food Sciences, 2004
At the present time the use of reliable control methods to ensure the labeled quality of food is task for organizations that have to limit or eliminate the falsification.
A. Trilčová   +6 more
doaj   +1 more source

Engineered Microbial Cell Factories for Sustainable Production of L-Lactic Acid: A Critical Review

open access: yesFermentation, 2022
With the increasing demand for the biodegradable polymer material polylactic acid and its advantage of being metabolized by the human body, L-lactic acid (L-LA) is becoming increasingly attractive in environmental protection and food industry ...
Tiantian Liu   +6 more
doaj   +1 more source

Combinatorial Metabolic Engineering and Enzymatic Catalysis Enable Efficient Production of Colanic Acid

open access: yesMicroorganisms, 2022
Colanic acid can promote the lifespan of humans by regulating mitochondrial homeostasis, and it has widespread applications in the field of health. However, colanic acid is produced at a low temperature (20 °C) with low titer. Using Escherichia coli K-12
Suwei Li   +6 more
doaj   +1 more source

Dermatan Sulfate: Structure, Biosynthesis, and Biological Roles

open access: yesBiomolecules
Dermatan sulfate (DS) is a remarkably versatile glycosaminoglycan that plays critical roles across a wide array of biological processes. Its unique structure, characterized by repeating disaccharide units of N-acetyl-D-galactosamine (GalNAc) and Iduronic
Congcong Chen   +7 more
doaj   +1 more source

Combinatorial pathway enzyme engineering and host engineering overcomes pyruvate overflow and enhances overproduction of N-acetylglucosamine in Bacillus subtilis

open access: yesMicrobial Cell Factories, 2019
Background Glucosamine-6-phosphate N-acetyltransferase (GNA1) is the key enzyme that causes overproduction of N-acetylglucosamine in Bacillus subtilis.
Wenlong Ma   +5 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Analysis of acid-tolerance mechanism based on membrane microdomains in Saccharomyces cerevisiae

open access: yesMicrobial Cell Factories, 2023
Background Saccharomyces cerevisiae has been used in the biosynthesis of acid products such as organic acids owing to its acid tolerance. Improving the acid tolerance of S. cerevisiae is beneficial for expanding its application range.
Xueqin Lv   +9 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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