Results 101 to 110 of about 186,975 (294)

Bifidobacterium Pseudolongum‐Derived Acetate Attenuates Acute Pancreatitis Through GPR43‐Mediated Suppression of M1 Macrophage Polarization

Advanced Science, EarlyView.
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan, Xueyang Li, Cong He, Pan Zheng, Yaoyu Zou, Qi Zhu, Xin Li, Jie Liang, Junmin Yang, Li Zhang, Yuman Ye, Jianhua Wan, Huajing Ke, Jianping Liu, Nonghua Lu, Nianshuang Li, Yin Zhu   +16 more
wiley   +1 more source

Metastatic prostate cancer with elevated serum levels of CEA and CA19-9

Urological Science, 2014
Prostate-specific antigen (PSA) is well known as a specific tumor marker for prostate cancer, but carcinoembryonic antigen (CEA)- and carbohydrate antigen 19-9 (CA19-9)-elevating adenocarcinomas originating in the prostate gland are rare.
Guang-Dar Juang, Thomas I.S. Hwang, Yuan-Hung Wang   +2 more
doaj   +1 more source

Evaluation of carbohydrate antigen 19-9 levels in subjects with diabetes mellitus in Nnamdi Azikiwe university teaching hospital, Nnewi, Nigeria

Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2020
Background of Study: Diabetes mellitus (DM) is a multisystemic disorder characterized by hyperglycemia and damage to vital organs most notably the exocrine tissue and islet cells.
P O Manafa, E C Okoye, O Ekuma-Okereke, R N Ukibe, C Ibe, C R Chukwuanukwu, O G Chukwuma, E K Nwene, S R Ebugosi, I V Manafa, C C Manafa   +10 more
doaj   +1 more source

The Bw4 public epitope of HLA-B molecules confers reactivity with natural killer cell clones that express NKB1, a putative HLA receptor. [PDF]

, 1995
Although inhibition of natural killer (NK) cell-mediated lysis by the class I HLA molecules of target cells is an established phenomenon, knowledge of the features of class I molecules which induce this effect remains rudimentary.
Gumperz, JE, Lanier, LL, Litwin, V, Parham, P, Phillips, JH   +4 more
core  

Alternative antibody for the detection of CA19-9 antigen: a European multicenter study for the evaluation of the analytical and clinical performance of the Access (R) GI Monitor assay on the UniCel (R) Dxl 800 Immunoassay System [PDF]

, 2008
Background: Gastrointestinal cancer antigen CA19-9 is known as a valuable marker for the management of patients with pancreatic cancer. Methods: The analytical and clinical performance of the Access(R) GI Monitor assay (Beckman Coulter) was evaluated on ...
Barone D, Bekaii-Saab TS, Dittadi R, Gogas H, Heinemann V, Ishii H, Jiang XT, Magnani JL, Micke O, Molina R, Reiter W, Reiter W, Safi F, Steinberg W, Tempero MA, Wang WS   +15 more
core   +3 more sources

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

Advanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang, Yufeng Xu, Yanfei Hu, Lijun Cao, Ru Jiang, Changtian Chen, Rick Masonbrink, Thomas Maier, Yuchen Tu, Yabo Shi, Enhui Liu, Lingan Kong, Chan Guo, Wei Zhao, Peng Shi, Wenzhen Du, Andrew Severin, Thomas Baum, Deliang Peng, Huan Peng, Mian Zhou, Wei Wang   +21 more
wiley   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

A Predictive Scoring System Based on Inflammatory and Tumor Markers for Gastric Cancer Patients Undergoing Curative Resection

Cancer Management and Research, 2020
Li-Wen Feng,1 Jing Li,1 Li-Feng Liang,2 Qian-Qian Guo,1 Jiang Li,3 Jian Wu,3 Pei-Hua Zhang,3 Yan-Ru Qin1 1Department of Oncology, Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, People’s Republic of China; 2Department of Internal ...
Feng LW, Li J, Liang LF, Guo QQ, Li J, Wu J, Zhang PH, Qin YR   +7 more
doaj  

Clinical use of tumor biomarkers in prediction for prognosis and chemotherapeutic effect in esophageal squamous cell carcinoma

BMC Cancer, 2019
Background Growing evidence has indicated that tumor biomarkers, including cytokeratin 19 fragment antigen 21–1 (Cyfra21–1), carbohydrate antigen 19–9 (CA19–9), carbohydrate antigen 72–4 (CA72–4), carcinoembryonic antigen (CEA) and squamous cell ...
Yuchong Yang, Xuanzhang Huang, Likun Zhou, Ting Deng, Tao Ning, Rui Liu, Le Zhang, Ming Bai, Haiyang Zhang, Hongli Li, Yi Ba   +10 more
doaj   +1 more source

High expression FUT1 and B3GALT5 is an independent predictor of postoperative recurrence and survival in hepatocellular carcinoma. [PDF]

, 2017
Cancer may arise from dedifferentiation of mature cells or maturation-arrested stem cells. Previously we reported that definitive endoderm from which liver was derived, expressed Globo H, SSEA-3 and SSEA-4.
Ho, Ming-Yi, Hsieh, Chung-Bao, Huang, Yen-Lin, Hung, Jung-Tung, Hung, Tsai-Hsien, Kuo, Huan-Hsien, Lin, Ruey-Jen, Lo, Fei-Yun, Yeh, Chau-Ting, Yu, Alice L, Yu, John   +10 more
core   +3 more sources