Results 201 to 210 of about 127,738 (290)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

FUT2 and FUT3-specific normalization of DUPAN-2 and carbohydrate antigen 19-9 in preoperative therapy for pancreatic cancer: multicentre retrospective study (GEMINI-PC-01). [PDF]

Br J Surg
Tanaka H, Sakai A, Suenaga M, Hayashi M, Otsu T, Nakagawa N, Kurimoto K, Fukasawa M, Shibuya K, Watanabe N, Sunagawa M, Yamaguchi J, Mizuno T, Kokuryo T, Takami H, Ebata T, Fujii T, Kodera Y.   +17 more
europepmc   +1 more source

Frequency and Correlates of Elevated Serum Carbohydrate Antigen 19-9 Levels in a Cohort of Nigerians with Type 2 Diabetes Mellitus

Abimbola O. Lawal, Jokotade O. Adeleye, Arinola Esan, Oyebola Oluwagbemiga Sonuga   +3 more
openalex   +1 more source

ASO Visual Abstract: Neoadjuvant Treatment with Changes in Chemotherapy Regimens According to Carbohydrate Antigen 19-9 Level for Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma [PDF]

Daisuke Hashimoto, Sohei Satoi, So Yamaki, Shinji Nakayama, Nobuhiro Shibata, Kazuki Matsumura, Hidetaka Miyazaki, Yuki Matsui, Denys Tsybulskyi, Nguyen Thanh Sang, Tsukasa Ikeura, Masashi Kanai, Mitsugu Sekimoto   +12 more
openalex   +1 more source

Redefining CHI3L1: Therapeutic Opportunities at the Crossroads of Immune Suppression and Disease Progression

Medicinal Research Reviews, EarlyView.
ABSTRACT Chitinase‐3‐like‐1 (CHI3L1, also known as YKL‐40) has been recognized as a biomarker of inflammation and tissue remodeling and has now emerged as a pseudoenzymatic immune checkpoint. Recent structural, immunological, and translational studies redefine it as an active regulator of immune suppression rather than a passive disease marker. Despite
Kirti Upmanyu, Saurabh Upadhyay, Moustafa T. Gabr   +2 more
wiley   +1 more source

Preoperative combined biomarker model of fibrinogen-to-albumin ratio and systemic immune-inflammation index to carbohydrate antigen 19-9 ratio predicts survival in distal cholangiocarcinoma after pancreatoduodenectomy: a retrospective cohort study. [PDF]

BMC Surg
Wang F, He Q, Lyu S.
europepmc   +1 more source

The Microbiome as a Mirror: Distinguishing Healthy Individuals From Chronic Constipated Patients and Identifying Those With Hidden Psychiatric Burden

Microbiota Medicine Research, EarlyView.
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi, Ting Yu, Weichen Liu, Ya Jiang, Die Chen, Li Gao, Hui Li, Yurong Tang   +7 more
wiley   +1 more source

Potential of Carbohydrate Antigen 19-9 and Serum Apolipoprotein A2-Isoforms in the Diagnosis of Stage 0 and IA Pancreatic Cancer. [PDF]

Diagnostics (Basel)
Hanada K, Shimizu A, Tsushima K, Kobayashi M.   +3 more
europepmc   +1 more source

膵癌術前治療におけるFUT2およびFUT3遺伝子型別のDUPAN-2およびcarbohydrate antigen 19-9の正常化の検討：多施設共同後ろ向き研究（GEMINI-PC-01） [PDF]

彩乃 酒井
openalex   +1 more source

Comparative analysis of alpha-fetoprotein, carbohydrate antigen 19-9, carcinoembryonic antigen, and prostate-specific antigen among conventional cigarette smokers, heated tobacco product users and quitters. [PDF]

Tob Induc Dis
Kim DH, Hong SW, Park N.
europepmc   +1 more source