Results 41 to 50 of about 17,427 (173)

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

A Phase 2 Trial of Frexalimab, a CD40L Antagonist, in Adolescents and Adults With Recent‐Onset Type 1 Diabetes (FABULINUS): Rationale and Study Design

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction Type 1 diabetes (T1D) is a chronic autoimmune disease, characterised by progressive destruction of the insulin‐producing pancreatic β‐cells. Preserving remaining β‐cells at the time of diagnosis may improve long‐term outcomes. Frexalimab is a humanised monoclonal antibody specific for CD40L undergoing evaluation for treatment of ...
Andriy Cherkas, Baerbel Rotthaeuser, Niels Porksen, Pascale Labard, My‐Liên Nguyên‐Pascal, Mathieu Coudert, Baptiste Berthou, Marie Baccara‐Dinet, Gabor Boka, Mark Peakman, Felix Reschke, Michael J. Haller   +11 more
wiley   +1 more source

Nutritional ketosis improves exercise metabolism in patients with very long‐chain acyl‐CoA dehydrogenase deficiency [PDF]

, 2020
A maladaptive shift from fat to carbohydrate (CHO) oxidation during exercise is thought to underlie myopathy and exercise-induced rhabdomyolysis in patients with fatty acid oxidation (FAO) disorders.
Monique G. M. de Sain‐van der Velden, Jeroen A. L. Jeneson, Bleeker, Jeannette C., de Sain-van der Velden, Monique GM, Cox, Pete J., Frits A. Wijburg, Langeveld, Mirjam, Tim Takken, Sibeijn-Kuiper, Anita, Wanders, Ronald JA, Jeannette C. Bleeker, de Sain-van der Velden, Monique G M, Lodewijk IJlst, van der Woude, Luc H, Visser, Gepke, Houtkooper, Riekelt H, Anita Sibeijn‐Kuiper, van Weeghel, Michel, Wanders, Ronald J. A., Mirjam Langeveld, Kok, Irene L, Wüst, Rob C. I., Ferdinandusse, Sacha, Bleeker, Jeannette C, van der Pol, W. Ludo, Irene L. Kok, de Haan, Ferdinand H, Takken, Tim, Jeneson, Jeroen AL, Kok, Irene L., Wüst, Rob C I, van der Woude, Luc H., Wanders, Ronald J.A., W. Ludo van der Pol, Wijburg, Frits A., Wüst, Rob C.I., Kieran Clarke, Jeneson, Jeroen A L, Wanders, Ronald J A, Jeneson, Jeroen A. L., Ferdinand H. de Haan, Rob C. I. Wüst, de Sain-van der Velden, Monique G.M., Cox, Pete J, Sacha Ferdinandusse, Michel van Weeghel, IJlst, Lodewijk, Ronald J. A. Wanders, van der Pol, W Ludo, de Haan, Ferdinand H., Gepke Visser, Luc H. van der Woude, Wüst, Rob CI, Wüst, Rob C I; id_orcid, de Sain-van der Velden, Monique G. M., van der Woude, Luc H; id_orcid, Wijburg, Frits A, Houtkooper, Riekelt H., Clarke, Kieran, Riekelt H. Houtkooper, Pete J. Cox, Jeneson, Jeroen A.L.   +61 more
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Maternal Hypoglycemia and Reduced Foetal Growth in Pregnancies Following Roux‐en‐Y Gastric Bypass: A Prospective Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Introduction The risk of delivering a small‐for‐gestational‐age (SGA) neonate is increased after Roux‐en‐Y gastric bypass (RYGB). Because glucose is the foetus's primary energy source and postprandial hypoglycemia is common after RYGB, the Bariatric surgery And consequences for Mother and Baby In pregnancy (BAMBI) study examined associations ...
Louise L. Stentebjerg, Lene R. Madsen, René K. Støving, Lise Lotte T. Andersen, Claus B. Juhl, Christina A. Vinter, Dorte M. Jensen   +6 more
wiley   +1 more source

Nutrition and medical support during pregnancy and lactation in women with inborn errors of intermediary metabolism disorders (IEMDs)

, 2020
The establishment of expanded newborn screening (NBS) not only results in the early diagnosis and treatment of neonates with inborn errors of intermediary metabolism disorders (IEMDs) but also helps the affected females to reach the reproductive age ...
Manta-Vogli, P.D., Dotsikas, Y., Loukas, Y.L., Schulpis, K.H.   +3 more
core  

Laboratory and Medicine 2.1: Care for What You Wish for

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Over the past few decades, healthcare has made remarkable advances. Across nearly all fields, diseases are better understood, and diagnostic and therapeutic options have expanded dramatically. Laboratory medicine is also developing at a rapid pace and is playing an increasingly central role in the diagnostic process, as well as in the ...
Marcel Levi
wiley   +1 more source

Protein consumption during pregnancy and risk of gestational diabetes mellitus: Insights from a multi‐center case–control study

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Aims Gestational diabetes mellitus (GDM) poses major health risks for mothers and infants. Evidence on the association between dietary protein intake and GDM risk remains inconsistent. This study investigated dietary protein quantity and quality in relation to GDM.
Marzieh Zare, Elnaz Daneshzad, Hatav Tehrani, Razieh Tabaeifard, Maryam Mahmoudi, Leila Azadbakht   +5 more
wiley   +1 more source

Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia

Journal of Sleep Research, EarlyView.
ABSTRACT Insomnia may play a causal role in type 2 diabetes (T2D). Addressing insomnia through cognitive behavioural therapy (CBTi) in people with non‐diabetic hyperglycaemia could potentially reduce the risk of progression to T2D. To inform a future randomised trial, we performed a feasibility study of digital CBT (dCBTi) in individuals at increased ...
Rachel Sharman, David Ray, Andrew Farmer, Poppy C. E. Green, Victoria Harris, Fredrik Karpe, Colin A. Espie, Diana Mantripp, Thomas Marjot, Niall M. McGowan, Jeremy W. Tomlinson, Simon D. Kyle   +11 more
wiley   +1 more source

The eye in metabolic diseases: clues to diagnosis

, 2011
Ophthalmologic manifestations occur in various inborn errors of metabolism (IEM), including small molecule disorders and organelle disorders. In a minority of diseases the occurrence of eye abnormalities could be attributed to direct toxic mechanisms of ...
Maillette de Buy Wenniger-Prick, C. J., C.J. Maillette de Buy Wenniger-Prick, Poll-The, B. T., B.T. Poll-The   +3 more
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The natural history of classic galactosemia: Lessons from the GalNet registry [PDF]

, 2019
Background: Classic galactosemia is a rare inborn error of carbohydrate metabolism, caused by a severe deficiency of the enzyme galactose-1-phosphate uridylyltransferase (GALT).
A. Coelho (6642644), Hubert, A., Langendonk, J G, Müller-Wieland, D., Derks, T; id_orcid, Moeslinger, D, M. Couce (6642647), K. M. Stepien, Forga, M. T.,, Berry, GT, Welsink-Karssies, M.M., Bosch, A.M., D. Ramadza (6642710), Häberle, J.,, T. Derks, Hochuli, M. (Michel), Eyskens, F.,, Derks, T.,, Scholl-Buergi, S., Berry, G T, J. Häberle, Demirbas, D., Mueller-Wieland, D, S. Wortmann (6642740), Waisbren, S. E.,, Rivera, I A, Welsink-Karssies, MM, Treacy, E. P., G. T. Berry, R. Vos, Couce, M L, Kotzka, J, Labrune, P., Huidekoper, H. H., Landau, Y. E.,, Visser, G.,, de Vries, M, Couce, ML, S. B. Wortmann, M. L. Couce, Murphy, E.,, Scholl-Buergi, S.,, Murphy, E, R. Vara (6642725), F. Eyskens, Burnytė, Birutė,, Knerr, I.,, Landau, Y E, G. Berry (5627070), A. I. Coelho, Janeiro, P, Wortmann, SB, M. Vries (6642731), Dawson, C, P. Janeiro (6642683), Wortmann, S.B. (S.), Ramadza, D., Müller-Wieland, D, Eyskens, F., B. Burnyte (6642641), I. A. Rivera, Vara, R.,, Eyskens, F, Waisbren, S E, Thijs, A., J. Kotzka (6642686), Stepien, K.M., Y. E. Landau, Hubert, A.,, A. Thijs, Dawson, C., Langendonk, J. G.,, E. Murphy (6642704), Coelho, A.I., Grünewald, S. (Sonja), S. Scholl-Buergi, Mueller-Wieland, D., Coelho, A. I., Couce, M. L., S. Waisbren (6642734), Demirbas, D.,, Thijs, A, Y. Landau (6642695), De Vries, M.,, Demirbas, D, Janeiro, P.,, Tran, C., Stepien, K M, Möslinger, D, Visser, G., Treacy, E P, D. MĂśslinger (6642761), Murphy, E. (Elaine), van den Bosch, A.M., R. Vos (6642728), Langendonk, Janneke, H. Huidekoper (6642680), D. Möslinger, Rubio-Gozalbo, M.E., Grunewald, S, C. Tran, M. Haskovic (6642635), Waisbren, S.E., E. Murphy, D. Ramadza, Möslinger, D., M. Forga (6642665), Forga, M.T., B. Burnyte, Huidekoper, Hidde; id_orcid, J. Langendonk (3466601), M. Haskovic, Tran, C.,, Cassiman, D, Waisbren, SE, Stepien, K. M., E. P. Treacy, M. Gautschi, Kotzka, J.,, D. Demirbas (6642656), Forga, MT, D. Müller-Wieland, Eyskens, F. (François), Gautschi, M., Knerr, I. (Ina), Cassiman, D., Derks, T, Coelho, A I, M. Hochuli (6642674), Wortmann, S.B., Häberle, J, Stepien, KM, Couce Pico, María de la Luz, Derks, T., Welsink-Karssies, M. M., Ramadza, D.,, C. Dawson (6642650), Gautschi, M. (Matthias), Dawson, C.,, P. Labrune (6642692), Huidekoper, H.H., Janeiro, P., M. Welsink-Karssies (6642737), Haskovic, M, Stepien, K. M.,, M. M. Welsink-Karssies, Õunap, K. (Katrin), Landau, YE, Forga, M. T., Cassiman, D.,, Moeslinger, D., J. Kotzka, Vos, R.,, Langendonk, J.G. (Janneke), Couce Pico, María Luz, Vara, R., K. Õunap, A. Thijs (6076467), Hochuli, M., Rivera, IA, Wortmann, S. B., Huidekoper, H H, T. Derks (6642659), Langendonk, Janneke; id_orcid, Bosch, A. M., G. Visser, Müller-Wieland, D.,, Bosch, A M, Berry, G.T., Rivera, I. A., Visser, G, Hochuli, M.,, Welsink-Karssies, M. M.,, P. Labrune, M. de Vries, Vos, Reinder, Grunewald, S., Forga, M T, S. Scholl-Buergi (6642716), S. Grunewald, Haskovic, M., de Vries, M., Burnyte, B., Grunewald, S.,, Eyskens, Fran\ue7ois, Gautschi, M.,, Huidekoper, Hidde, Berry, G. T.,, K. Stepien (6642719), Couce, M. L.,, Vos, R., Õunap, K.,, Thijs, A.,, Berry, G. T., Burnyte, B, D. MĂźller-Wieland (6642767), Landau, Y. E., Rivera, I.A., Vos, R, K. Õunap (6642773), Langendonk, J. G., Treacy, E. P.,, Langendonk, J.G., J. Häberle (6642749), Vries, M. (Marieke) de, A. M. Bosch, Vos, R.O., Murphy, E., Õunap, K, Kotzka, J., Hochuli, M, M. Rubio-Gozalbo (6642629), Bosch, A. M.,, Labrune, P, D. Cassiman (3567683), H. H. Huidekoper, M. Hochuli, I. Rivera (6642713), Coelho, AI, Rubio-Gozalbo, M E, E. Treacy (6642746), Waisbren, S. E., Welsink-Karssies, M M, R. Vara, Õunap, K., Treacy, EP, S. E. Waisbren, Möslinger, D.,, Rivera, I. A.,, S. Grunewald (6642668), P. Janeiro, Treacy, E.P., I. Knerr, Knerr, I, Wortmann, S B, Vara, R, M. Gautschi (6642743), Tran, C, Hubert, A, Couce, M.L., C. Tran (6642722), M. T. Forga, Landau, Y.E., D. Cassiman, Rubio-Gozalbo, M.E. (Estela), Rubio-Gozalbo, M. E., G. Visser (1808224), Haskovic, M.,, Coelho, A. I.,, Ramadza, D, Huidekoper, H. H.,, Wortmann, S. B.,, Bosch, AM, Gautschi, Matthias, F. Eyskens (6642662), J. G. Langendonk, Vries, M, A. Hubert (6642677), I. Knerr (6642689), Häberle, J. (Johannes), A. Bosch (6642638), Rubio-Gozalbo, M. E.,, Scholl-Buergi, S, M. E. Rubio-Gozalbo, C. Dawson, Labrune, P.,, D. Demirbas, Gautschi, M, Rubio-Gozalbo, ME, A. Hubert, Häberle, J., Knerr, I.   +271 more
core   +1 more source