A Dual-Hormone Closed-Loop Delivery System for Type 1 Diabetes Using Deep Reinforcement Learning [PDF]
We propose a dual-hormone delivery strategy by exploiting deep reinforcement learning (RL) for people with Type 1 Diabetes (T1D). Specifically, double dilated recurrent neural networks (RNN) are used to learn the hormone delivery strategy, trained by a variant of Q-learning, whose inputs are raw data of glucose \& meal carbohydrate and outputs are dual-
arxiv
Banana skin: a novel material for a low-cost production of laccase [PDF]
Laccases (benzenodiol: oxygen oxidoreductases; EC 1.10.3.2) are multicopper oxidases of wide substrate specificity mainly found in white-rot fungi, which are the only microorganisms able to degrade the whole wood components, but they are also expressed in bacteria and higher plants. Laccases are used currently in biotechnological processes because this
arxiv
UROĐENE BOLESTI METABOLIZMA UGLJIKOHIDRATA, AMINOKISELINA I MASNIH KISELINA
Urođene metaboličke bolesti velika su skupina genetičkih i biokemijskih poremećaja metabolizma koje se najčešće nasljeđuju prema Mendelovim zakonima nasljeđivanja, a uzrokovane su mutacijama gena koji kodiraju određene enzime ili transportere, što je izraženo u bolestima u metabolizmu ugljikohidrata, aminokiselina i masnih kiselina.
openaire +2 more sources
Milestones at the Origin of Life [PDF]
Living organisms have some common structures, chemical reactions and molecular structures. The organisms consist of cells with cell division, they have homochirality of protein and carbohydrate units, and metabolism, and genetics, and they are mortal. The molecular structures and chemical reactions underlying these features are common from the simplest
arxiv
Direct imaging of carbohydrate stereochemistry [PDF]
Carbohydrates, essential biological building blocks, exhibit functional mechanisms tied to their intricate stereochemistry. Subtle stereochemical differences, such as those between the anomers maltose and cellobiose, lead to distinct properties due to their differing glycosidic bonds; the former is digestible by humans, while the latter is not.
arxiv
Out-of-pocket health expenditures in patients living with ınborn errors of metabolism. [PDF]
Gündüz M+2 more
europepmc +1 more source
Metabolomic profiles in Jamaican children with and without autism spectrum disorder [PDF]
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with a wide range of behavioral and cognitive impairments. While genetic and environmental factors are known to contribute to its etiology, the underlying metabolic perturbations associated with ASD which can potentially connect genetic and environmental factors, remain poorly ...
arxiv
Ocular Manifestations of Inborn Errors of Carbohydrate and Lipid Metabolism (Bibliotheca Ophthalmologica No. 84) [PDF]
openaire +2 more sources
Hormonal Crossroads in Inborn Errors of the Metabolism Impact of Puberty and Dietary Interventions on Metabolic Health. [PDF]
Lundqvist T, Stenlid R, Halldin M.
europepmc +1 more source
A Review of Disparities and Unmet Newborn Screening Needs over 33 Years in a Cohort of Mexican Patients with Inborn Errors of Intermediary Metabolism. [PDF]
Ibarra-González I+7 more
europepmc +1 more source