This work presents a computational–experimental strategy to engineer material‐binding peptides toward polymer specificity. Molecular dynamics simulations identified residues driving polystyrene binding, enabling targeted substitutions that greatly reduced polystyrene affinity while preserving PET binding.
Julian Luka +3 more
wiley +1 more source
Widespread dissemination of the RepA_N-type megaplasmid conferring a carbohydrate utilization advantage in clonal complex 17 <i>Enterococcus faecium</i> in Taiwan. [PDF]
Chen Y-J +7 more
europepmc +1 more source
ABSTRACT Translating dynamic liquid‐liquid phase separation into robust solid‐state architectures remains a challenge in materials engineering. Here, we report a composition‐driven interfacial assembly strategy that couples supramolecular coacervation with metal‐phenolic coordination to engineer tunable fungicide carriers.
Rui Zhang +7 more
wiley +1 more source
Predictions from deep learning propose substantial protein-carbohydrate interplay. [PDF]
Canner SW, Schnaar RL, Gray JJ.
europepmc +1 more source
BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li +8 more
wiley +1 more source
Human α1‐antitrypsin: carbohydrate attachment and sequence homology
Carrell, R.W. +5 more
openaire +2 more sources
A Food-Based Sequential KETOgenic Nutritional Protocol for Mediterranean Diet Non-Responders with COMPlicated Obesity: A Real-World Observational Study (KETOCOMP). [PDF]
Romano M +10 more
europepmc +1 more source
Comparative antennal single‐nucleus transcriptomics reveals cell‐type‐dependent transcriptomic divergence in Bactrocera dorsalis, with similar structural cells but divergent sensory neurons. This neuronal diversification is associated with a distinct ammonia‐sensing pathway, linking female attraction to bird‐dropping‐associated cues with nutritional ...
Wei Liu +7 more
wiley +1 more source
Complete genome sequence of <i>Bifidobacterium longum</i> subsp. <i>longum</i> strain iVE-15. [PDF]
Van Haute MJ +5 more
europepmc +1 more source
Canonical Antibodies Adopt Distinct Binding Modes to Recognize Viral Glycan Shields
Canonical Y‐shaped antibodies recognize viral glycan shields through adaptive Fab assembly states shaped by glycan organization and somatic hypermutation. Structural analyses ofbroadly neutralizing antibodies VRC35 and VRC36 across glycoproteins of HIV‐1, influenza, SARS‐CoV‐2, and Lassa viruses reveal distinct Fab assembly states, spanning monovalent,
Jiaxuan Cheng +71 more
wiley +1 more source

