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Advancing Solutions to the Carbohydrate Sequencing Challenge [PDF]
Carbohydrates possess a variety of distinct features with stereochemistry playing a particularly important role in distinguishing their structure and function. Monosaccharide building blocks are defined by a high density of chiral centers. Additionally, the anomericity and regiochemistry of the glycosidic linkages carry important biological information.
Christopher J. Gray +10 more
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The carbohydrate sequence markup language (CabosML): an XML description of carbohydrate structures [PDF]
Bioinformatics resources for glycomics are very poor as compared with those for genomics and proteomics. The complexity of carbohydrate sequences makes it difficult to define a common language to represent them, and the development of bioinformatics tools for glycomics has not progressed.
Norihiro Kikuchi +7 more
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Acetylated glucuronoxylan is one of the most common types of hemicellulose in nature. The structure is formed by a β-(1→4)-linked D-xylopyranosyl (Xylp) backbone that can be substituted with an acetyl group at O-2 and O-3 positions, and α-(1→2)-linked 4 ...
Leena Penttinen +6 more
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Uncultured microbes represent a huge untapped biological resource of novel genes and gene products. Although recent genomic and metagenomic sequencing efforts have led to the identification of numerous genes that are homologous to existing annotated ...
Akil Akhtar +6 more
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Meiofauna at a tropical sandy beach in the SW Atlantic: the influence of seasonality on diversity [PDF]
Background Sandy beaches are dynamic environments housing a large diversity of organisms and providing important environmental services. Meiofaunal metazoan are small organisms that play a key role in the sediment.
Gabriel C. Coppo +3 more
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Carbohydrate sequence of a soybean 7S protein.
The sequences of three Asn-carbohydrates, IIa, Asn(GlcNAc)2-(Man)9; IIb, Asn(GlcNAc)2(Man)8; and IIc, Asn(GlcNAc)2(Man)7 isolated from the pronase digest of a 7S soybean protein (β-conglycinin) were investigated. In each case, methylation analysis of the Asn-carbohydrates gave 3, 6-di-O-methyl derivative from the N-acetyl-glucosamine residue, and 2, 3,
YAMAUCHI, Fumio, YAMAGISHI, Tatsunori
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Background Omics approaches are widely applied in the field of biology for the discovery of potential CAZymes including whole genome sequencing. The aim of this study was to identify protein encoding genes including CAZymes in order to understand glycans-
Rihab Ameri +9 more
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Structural similarity of the terminal carbohydrate sequences of glycoproteins and glycolipids [PDF]
The carbohydrate chains of animal cell membranes are covalently lmked to either protein or lipid. Both glycoproteins and glycohprds are asymmetrically onented m cell membranes, with then saccharide chains projecting outwards from the membrane [ 13. The carbohydrate chains of both classes of glycocomugates have been suggested to be involved in many cell
Rauvala, Heikki, Finne, Jukka
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Galectins: a key intersection between glycobiology and immunology
Galectins are a family of evolutionarily conserved animal lectins, widely distributed from lower invertebrates to mammals. They share sequence and structure similarities in the carbohydrate recognition domain and specificity for polylactosamine-enriched ...
G.A. Rabinovich +3 more
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The giant African snail (Order Stylommatophora: Family Achatinidae), Achatina fulica (Bowdich, 1822), is the most significant and invasive land snail pest.
Pornpavee Nualnisachol +2 more
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