Results 231 to 240 of about 7,863,983 (293)

Feasibility of planar myocardial carbon 11-acetate imaging

Journal of Nuclear Cardiology, 2000
Myocardial oxygen consumption can be determined by using carbon 11-acetate (11C-acetate) and positron emission tomography (PET). The aim of this study was to validate planar 11C-acetate scintigraphy in healthy individuals by relating the myocardial clearance rate of dynamic 11C-acetate scintigraphy with the rate-pressure product, which is used as a ...
L J, Klein, F C, Visser, S A, Nurmohamed, A, Vink, J H, Peters, P, Knaapen, P S, Kruijer, J D, Herscheid, G J, Teule, C A, Visser   +9 more
openaire   +2 more sources

Imaging Myocardium Enzymatic Pathways with Carbon-11 Radiotracers

2004
Publisher Summary This chapter elaborates the imaging of myocardium enzymatic pathways with carbon-11 radiotracers. Under normal conditions, the heart utilizes a variety of metabolic pathways, such as the oxidation of carbohydrates, fatty acids, lactate, and pyruvate, to meet the high-energy demands of contraction and maintenance of cellular function.
Carmen S, Dence, Pilar, Herrero, Sally W, Schwarz, Robert H, Mach, Robert J, Gropler, Michael J, Welch   +5 more
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Evaluation of Carbon-11 Labelled Phenylglycine and Phenylalanine for Pancreas Scintigraphy

Nuklearmedizin, 1975
SummaryCarbon-11 (t½ = 20.4 min, β+) labelled DL-α-phenylalanine and DL-α-phenylglycine were administered intravenously to rats and the distribution of the radioactive amino acids over pancreas, liver, spleen, kidneys and blood was measured after several time intervals.
VAALBURG, W, BEERLINGVANDERMOLEN, HD, WOLDRING, MG   +2 more
openaire   +3 more sources

Relationship of molecular structure to in vivo distribution of carbon-11-labeled compounds

European Journal of Nuclear Medicine, 1980
Six 11C-labeled aliphatic diamines containing 4–9 linear carbon atoms were synthesized in radiochemical yields of 57% to 84% by reduction of the intermediate 11C-dinitriles prepared from Na 11CN and the corresponding bromonitrile or dibromoalkane. The biodistribution of each 11C-diamine was studied in male Sprague-Dawley rats.
M B, Winstead, D D, Dischino, N A, Munder, C, Walsh, H S, Winchell   +4 more
openaire   +2 more sources

A new synthesis of carbon-11 labelled phosgene

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, 1987
Abstract [11C]Phosgene is an important precursor in the 11C labelling of certain medically useful molecules. Phosgene allows a carbonyl function to be inserted between two stereo-chemically close amino functions. Until now, [11C]phosgene has been synthesized from [11C]carbon dioxide.
P. Landais, C. Crouzel
openaire   +1 more source

Reactions of recoiling carbon-11 atoms with toluene

The Journal of Physical Chemistry, 1986
Formation of benzocyclobutene, a characteristic rearrangement product of tolylmethylenes, strongly suggests that these species are formed as intermediates in the reactions of recoiling carbon-11 atoms and toluene. Degradation and additive studies indicated that both singlet and triplet carbon atoms can lead to benzocyclobutene formation through ...
Peter P. Gaspar, David M. Berowitz, Daniel R. Strongin, Daniel L. Svoboda, Matthew B. Tuchler, Richard A. Ferrieri, Alfred P. Wolf   +6 more
openaire   +1 more source

Synthesis of carbon‐11 labelled (R)‐carnitine

Journal of Labelled Compounds and Radiopharmaceuticals, 1991
AbstractA route to 11C‐labelled (R)‐carnitine (1), based on the methylation of the dimethyl derivative (2) is described. Furthermore, a five‐step synthesis for the enantiomerically pure precursor (2) is outlined.
M. Holschbach, W. Hamkens, W. Roden, L. E. Feinendegen   +3 more
openaire   +1 more source

Carbon-11 and radiopharmaceuticals

The International Journal of Applied Radiation and Isotopes, 1977
A P, Wolf, C S, Redvanly
openaire   +2 more sources

In vivo demonstration of enzyme activity in endocrine pancreatic tumors: decarboxylation of carbon-11-DOPA to carbon-11-dopamine.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996
We used PET to characterize the uptake and decarboxylation of 11C-L-DOPA in vivo in two patients with endocrine pancreatic tumors: one glucagonoma and one gastrinoma.With L-DOPA labeled with 11C in the beta position, in which the radioactive label follows the molecule through decarboxylation to dopamine, significant uptake was observed in the tumors ...
M, Bergström, B, Eriksson, K, Oberg, A, Sundin, H, Ahlström, K J, Lindner, P, Bjurling, B, Långström   +7 more
openaire   +1 more source

Carbon-11 Amino Acids, Labeling and Metabolites

1993
The preparation methods available for 11C-amino acids and the different aspects of the value of these amino acids for measuring the protein synthesis rate in vivo are discussed.
Willem Vaalburg, Philip H. Elsinga, Anne M. J. Paans   +2 more
openaire   +1 more source