Results 1 to 10 of about 952,415 (264)
Hyperpolarized Carbon-13 MRI in Breast Cancer [PDF]
Diagnostics, 2023 One of the hallmarks of cancer is metabolic reprogramming, including high levels of aerobic glycolysis (the Warburg effect). Pyruvate is a product of glucose metabolism, and 13C-MR imaging of the metabolism of hyperpolarized (HP) [1-13C]pyruvate (HP 13C ...
Ramona Woitek, Kevin M. Brindle
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Comprehensive Literature Review of Hyperpolarized Carbon-13 MRI: The Road to Clinical Application [PDF]
Metabolites, 2021 This review provides a comprehensive assessment of the development of hyperpolarized (HP) carbon-13 metabolic MRI from the early days to the present with a focus on clinical applications.
Michael Vaeggemose +2 more
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MRI Application and Challenges of Hyperpolarized Carbon-13 Pyruvate in Translational and Clinical Cardiovascular Studies: A Literature Review [PDF]
DiagnosticsCardiovascular disease shows, or may even be caused by, changes in metabolism. Hyperpolarized magnetic resonance spectroscopy and imaging is a technique that could assess the role of different aspects of metabolism in heart disease, allowing real-time ...
Francesca Frijia +6 more
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Metabolites, 2023 Efficient 13C hyperpolarization of ketoisocaproate is demonstrated in natural isotopic abundance and [1-13C]enriched forms via SABRE-SHEATH (Signal Amplification By Reversible Exchange in SHield Enables Alignment Transfer to Heteronuclei).
Isaiah Adelabu +9 more
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Multivariate analysis of stable isotope data in the traceability process for birds=Análise multivariada em dados de isótopos estáveis no processo de rastreabilidade em aves [PDF]
Acta Scientiarum: Animal Sciences, 2012 Isotope analysis has proved to be an extremely important tool in the traceability process; however, statistical analyses of the results show discrepancies, as the data depend on and originate from several chemical elements such as carbon, hydrogen ...
Maria Márcia Pereira Sartori +4 more
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Elucidation of Lignin and Polysaccharide Linkages in Wheat Straw by 2H/13C Isotopic Tracer
BioResources, 2022 To elucidate chemical linkages between lignin and polysaccharides, the aqueous mixed solutions of coniferin-[α-13C], syringin-[α-13C], D-glucose-[6-2H], and phenylalanine ammonia-lyase inhibitor were injected into a living wheat stalk.
Yimin Xie +4 more
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Frontiers in Ecology and Evolution, 2023 Insect species that are nectivorous as adults acquire essential fatty acids almost exclusively from host plants during larval development. Thus, as essential fatty acids are important for a number of different biological processes, adult allocation of ...
Libesha Anparasan +3 more
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Inhibiting Glycine Decarboxylase Suppresses Pyruvate-to-Lactate Metabolism in Lung Cancer Cells
Frontiers in Oncology, 2018 Glycine decarboxylase (GLDC) gene is frequently upregulated in various types of cancer including lung, prostate and brain. It catabolizes glycine to yield 5,10-methylenetetrahydrofolate, an important substrate in one-carbon metabolism for nucleotide ...
Chern Chiuh Woo +4 more
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Metabolites, 2021 This study uses dynamic hyperpolarized [1-13C]pyruvate magnetic resonance spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between highly metastatic (4T1, n = 7) and metastatically dormant (4T07, n = 7) murine breast cancer ...
Erin B. Macdonald +9 more
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Pesquisa Agropecuária Brasileira, 2007 O objetivo deste estudo foi avaliar a influência da glutamina no turnover do carbono do tecido adiposo de leitões. Quarenta leitões foram desmamados aos 21 dias e distribuídos, aleatoriamente, em dois tratamentos: T1, dieta de plantas C3, sem ...
Fabiana Ribeiro Caldara +5 more
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