Results 31 to 40 of about 952,415 (264)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Hyperpolarized [2–13C]pyruvate MR molecular imaging with whole brain coverage

NeuroImage, 2023
Hyperpolarized (HP) 13C Magnetic Resonance Imaging (MRI) was applied for the first time to image and quantify the uptake and metabolism of [2–13C]pyruvate in the human brain to provide new metabolic information on cerebral energy metabolism.
Brian T. Chung, Yaewon Kim, Jeremy W. Gordon, Hsin-Yu Chen, Adam W. Autry, Philip M. Lee, Jasmine Y. Hu, Chou T. Tan, Chris Suszczynski, Susan M. Chang, Javier E. Villanueva-Meyer, Robert A. Bok, Peder E.Z. Larson, Duan Xu, Yan Li, Daniel B. Vigneron   +15 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Efeito da glutamina sobre o turnover do carbono (d13C) de músculos e vísceras de leitões desmamados: glutamina e turnover de carbono tecidual = Effect of glutamine on carbon (d13C) turnover in the muscles and viscera of weaned piglets

Acta Scientiarum: Animal Sciences, 2008
O estudo foi conduzido para verificar a influência da glutamina no turnover do carbono em tecidos de leitões. Nove porcas foram cobertas e receberam dietas compostas predominantemente por grãos de plantas do ciclo fotossintético C4 durante gestação e ...
Fabiana Ribeiro Caldara, Carlos Ducatti, Dirlei Antonio Berto, Juliana Célia Denadai, Evandro Tadeu da Silva, Rodrigo Garófallo Garcia   +5 more
doaj  

Evaluation of Sorbitol as an Endogenous Isotopic Reference Marker Compound for the Detection of C4-Type Sugar Adulteration in Apple Juice

Chemistry
Apple juice is one of the world’s most widely consumed fruit juices and is therefore a common target for economically motivated adulteration (EMA). Such adulteration may involve dilution with water, substitution with other juices, or the addition of ...
Mike Seed, Philipp I. Schodder, Marco Schmidt, Hesham Abdallah, Mikko Hofsommer, Simon Kelly, Jan Hartwig   +6 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Glutamina e turnover do carbono da mucosa intestinal de leitões desmamados Glutamine and carbon turnover of the intestinal mucosa of weaned piglets

Revista Brasileira de Zootecnia, 2010
Um experimento foi conduzido para verificar a influência da glutamina no turnover do carbono na mucosa intestinal de leitões desmamados. Nove matrizes receberam dietas compostas basicamente de plantas do ciclo fotossintético C4 durante toda a gestação (d&
Fabiana Ribeiro Caldara, Carlos Ducatti, Dirlei Antonio Berto, Juliana Célia Denadai, Rodrigo Garófallo Garcia, Viviane Maria Oliveira dos Santos Ferreira   +5 more
doaj   +1 more source

Carbon-13 NMR Spectra of Carotenoids [PDF]

Pure and Applied Chemistry, 1976
Abstract
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Aplicação dos isótopos estáveis em aqüicultura Stable isotopes in aquaculture

Revista Brasileira de Zootecnia, 2007
O produto mais importante do conhecimento é a ignorância. A situação sugere a imagem de alguém que vive numa ilha de conhecimento cercado por um mar de ignorância.
Carlos Ducatti
doaj   +1 more source