Results 51 to 60 of about 5,644,306 (315)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Carbon-13 NMR Spectra of Cotylenins

open access: yesAgricultural and Biological Chemistry, 1979
(1979). Carbon-13 NMR Spectra of Cotylenins. Agricultural and Biological Chemistry: Vol. 43, No. 2, pp. 385-387.
SASSA, Takeshi, TAKAHAMA, Akihiro
openaire   +2 more sources

Boundary layer chemical vapor synthesis of self-organized radial filled-carbon-nanotube structures

open access: yes, 2013
We report a new chemical vapor synthesis method that exploits random fluctuations in the viscous boundary layer between a laminar vapor flow and a surface to yield a not previously observed product: radial ferromagnetically filled-carbon-nanotube ...
Baxendale, M.   +5 more
core   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Retention of C-14-labeled multiwall carbon nanotubes by humic acid and polymers: Roles of macromolecule properties

open access: yes, 2016
Developing methods to measure interactions of carbon nanotubes (CNTs) with soils and sediments and understanding the impact of soil and sediment properties on CNT deposition are essential for assessing CNT environmental risks.
Xing, Baoshan   +13 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Synthesis of carbon-13-labeled tetradecanoic acids.

open access: yesJournal of Lipid Research, 1983
The synthesis of tetradecanoic acid enriched with 13C at carbons 1, 3, or 6 is described. The label at the carbonyl carbon was introduced by treating 1-bromotridecane with K13CN (90% enriched) to form the 13C-labeled nitrile, which upon hydrolysis ...
J T Sparrow, K M Patel, J D Morrisett
doaj   +1 more source

Carbon isotope anomaly in the major plant C-1 pool and its global biogeochemical implications

open access: yes, 2004
We report that the most abundant C-1 units of terrestrial plants, the methoxyl groups of pectin and lignin, have a unique carbon isotope signature exceptionally depleted in C-13.
Kalin, R.   +4 more
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Carbon footprints of 13 000 cities

open access: yesEnvironmental Research Letters, 2018
While it is understood that cities generate the majority of carbon emissions, for most cities, towns, and rural areas around the world no carbon footprint (CF) has been estimated.
Daniel Moran   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy