Results 61 to 70 of about 955,121 (302)
Carbon-13 NMR Spectra of Cotylenins
Agricultural and Biological Chemistry, 1979 (1979). Carbon-13 NMR Spectra of Cotylenins. Agricultural and Biological Chemistry: Vol. 43, No. 2, pp. 385-387.
Takeshi SASSA, Akihiro TAKAHAMA
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Differential Dynamics at Glycosidic Linkages of an Oligosaccharide as Revealed by 13C NMR Spin Relaxation and Stochastic Modeling [PDF]
, 2018 Among biomolecules, carbohydrates are unique in that not only can linkages be formed through different positions but the structures may also be branched.
Abragam A. +6 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Carbon-13 NMR Spectra of Carotenoids [PDF]
Pure and Applied Chemistry, 1976 Abstract
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Coastal climate reflected in carbon-13/carbon-12 ratio of organic carbon in varved sediment from Santa Barbara basin [PDF]
, 1991 A 1844-1987 time-series of carbon stable isotope ratios from dated sedimentary total organic carbon from the center of the Santa Barbara basin is compared with historical climate and oceanographic records.
Schimmelmann, Arndt, Tegner, Mia J.
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Synthesis of carbon-13-labeled tetradecanoic acids.
Journal of Lipid Research, 1983 The synthesis of tetradecanoic acid enriched with 13C at carbons 1, 3, or 6 is described. The label at the carbonyl carbon was introduced by treating 1-bromotridecane with K13CN (90% enriched) to form the 13C-labeled nitrile, which upon hydrolysis ...
J T Sparrow, K M Patel, J D Morrisett
doaj +1 more source