Results 61 to 70 of about 1,418,308 (344)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Improving the Satellite-Based Winter Wheat Monitoring by Using UAV-Derived Leaf Chlorophyll Content

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Mapping regional leaf chlorophyll content (LCC) still faces challenges of the scale mismatch between ground sampling points and satellite pixels. To improve the satellite-based model, this study explored the potential of using high-resolution unmanned ...
Jiale Jiang   +4 more
doaj   +1 more source

Bacteriophages as a model for studying carbon regulation in aquatic system [PDF]

open access: yes, 2012
The interconversion of carbon in organic, inorganic and refractory carbon is still beyond the grasp of present environmentalists. The bacteria and their phages, being the most abundant constituents of the aquatic environment, represent an ideal model for
Sandhya Swaminathan   +3 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

Extreme drought–accelerated dissolved carbon metabolism triggers pulsed CO2 outgassing in karst lakes [PDF]

open access: yesHydrology and Earth System Sciences
Karst aquatic ecosystems are important reservoirs of dissolved carbon (C), supporting dynamic CO2 fluxes through the biological C pump. However, our current understanding of how sophisticated interactions between aquatic microbiomes and dissolved C ...
M. Ni   +8 more
doaj   +1 more source

Terrestrial Carbon Cycle Variability [PDF]

open access: yesF1000Research, 2016
A growing literature is reporting on how the terrestrial carbon cycle is experiencing year-to-year variability because of climate anomalies and trends caused by global change. As CO2 concentration records in the atmosphere exceed 50 years and as satellite records reach over 30 years in length, we are becoming better able to address carbon cycle ...
Baldocchi, Dennis   +2 more
openaire   +4 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Global Wetland Methane Emissions From 2001 to 2020: Magnitude, Dynamics and Controls

open access: yesEarth's Future
The large uncertainties in estimating CH4 emissions from wetland ecosystems, the leading natural source to the atmosphere, substantially hinder the quantification of the global CH4 budget.
Han Xiao   +6 more
doaj   +1 more source

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