Results 81 to 90 of about 3,160,535 (395)

The Role of N2 as a Geo-Biosignature for the Detection and Characterization of Earth-like Habitats [PDF]

open access: yes, 2019
Since the Archean, N2 has been a major atmospheric constituent in Earth's atmosphere. Nitrogen is an essential element in the building blocks of life, therefore the geobiological nitrogen cycle is a fundamental factor in the long term evolution of both ...
Cubillos, Patricio E.   +6 more
core   +2 more sources

Heterotrophic Carbon Fixation in a Salamander-Alga Symbiosis

open access: yesbioRxiv, 2020
The unique symbiosis between a vertebrate salamander, Ambystoma maculatum, and unicellular green alga, Oophila amblystomatis, involves multiple modes of interaction. These include an ectosymbiotic interaction where the alga colonizes the egg capsule, and
J. Burns, Ryan Kerney, S. Duhamel
semanticscholar   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

A Possible Primordial Acetyleno/Carboxydotrophic Core Metabolism

open access: yesLife, 2020
Carbon fixation, in addition to the evolution of metabolism, is a main requirement for the evolution of life. Here, we report a one-pot carbon fixation of acetylene (C2H2) and carbon monoxide (CO) by aqueous nickel sulfide (NiS) under hydrothermal (>100 °
Jessica Sobotta   +6 more
doaj   +1 more source

Sphagnum physiology in the context of changing climate: emergent influences of genomics, modelling and host-microbiome interactions on understanding ecosystem function. [PDF]

open access: yes, 2014
Peatlands harbour more than one-third of terrestrial carbon leading to the argument that the bryophytes, as major components of peatland ecosystems, store more organic carbon in soils than any other collective plant taxa. Plants of the genus Sphagnum are
Gu, Lianhong   +9 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Long-term effects of a one-time application of flue gas desulfurization gypsum on the soil pore structure in sodic paddy fields

open access: yesAgricultural Water Management
Saline–sodic soil suffer from a high content of exchangeable sodium ions in the soil colloid and the poor air and water permeability of the soil pore structure.
Jianzhong Guo   +9 more
doaj   +1 more source

Evaluation of Carbon Fixation Potential and Analysis of Influencing Factors of Marine Microorganisms in the Beibu Gulf Based on Metagenomics [PDF]

open access: yesProgress in Fishery Sciences
Marine microorganisms, though microscopic, represent a vast reservoir of organic carbon and play a central role in element cycling and energy flow within marine ecosystems. As key contributors to the biogeochemical cycling of carbon, these microorganisms
GONG Chen   +7 more
doaj   +1 more source

Hydrothermal activity lowers trophic diversity in Antarctic sedimented hydrothermal vents [PDF]

open access: yes, 2016
Sedimented hydrothermal vents are those in which hydrothermal fluid vents through sediment and are among the least studied deep-sea ecosystems. We present a combination of microbial and biochemical data to assess trophodynamics between and within ...
Bell, James B.   +6 more
core   +1 more source

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