Results 161 to 170 of about 21,417 (198)

Tumor therapy with high-energy carbon ion beams

Nuclear Physics A, 2007
Heavy-ion beams offer favourable conditions for the treatment of deep-seated local tumors. The well defined range and the small lateral beam spread make it possible to deliver the dose with millimeter precision by applying advanced beam scanning techniques. In addition, heavy ions have an enhanced biological effectiveness in the Bragg peak region which
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Beam Dynamics Studies for a Compact Carbon Ion Linac for Therapy

2017
Proceedings of the 28th Linear Accelerator Conf., LINAC2016, East Lansing, MI ...
Plastun, Alexander, Faillace, Luigi, Kutsaev, Sergey, Mustapha, Brahim, Nassiri, Ali, Ostroumov, Peter, Savin, Evgeny   +6 more
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Radio-fluorogenic nanoclay gel dosimeters with reduced linear energy transfer dependence for carbon-ion beam radiotherapy.

Medical Physics (Lancaster), 2022
PURPOSE The precise assessment of the dose distribution of high linear energy transfer (LET) radiation remains a challenge, since the signal of most dosimeters will be saturated due to the high ionization density.
T. Maeyama, A. Mochizuki, Kazuki Yoshida, N. Fukunishi, K. Ishikawa, S. Fukuda   +5 more
semanticscholar   +1 more source

Monte Carlo computation of 3D distributions of stopping power ratios in Light Ion Beam Therapy using GATE-RTion.

Medical Physics (Lancaster), 2021
PURPOSE This paper presents a novel method for the calculation of 3D Bragg-Gray water-to-detector stopping power ratio (sw,det ) distributions for proton and carbon ion beams.
M. Bolsa-Ferruz, H. Palmans, D. Boersma, M. Stock, L. Grevillot   +4 more
semanticscholar   +1 more source

Experimental and theoretical study of the neutron dose produced by carbon ion therapy beams

Radiation Protection Dosimetry, 2007
High-energy (12)C ions offer favourable conditions for the treatment of deep-seated local tumours. Several facilities for the heavy ion therapy are planned or under construction, for example the new clinical ion-therapy unit HIT at the Radiological University Clinics in Heidelberg. In order to improve existing treatment planning models, it is essential
H, Iwase, K, Gunzert-Marx, E, Haettner, D, Schardt, F, Gutermuth, M, Kraemer, G, Kraft   +6 more
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Assessment of relative merits of proton and carbon ion beam therapy

2009
Objectives: Assess efficacy of proton and carbon ion therapy. Methods: Evaluate the rationale, physical, biological and clinical data base for 1H and 12C therapy. Results: The bases for interest in 1H and 12C therapy are the potential of: superior dose distributions for nearly all sites [for full text, please go to the a.m. URL]
Suit, H, Clasie, B, DeLaney, T, Flanz, J, Gerweck, L, Goldberg, S, Kooy, H, Niemierko, A, Paganetti, H, Trofimov, A   +9 more
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Investigations on novel imaging techniques for ion beam therapy: Carbon ion radiography and tomography

2011 IEEE Nuclear Science Symposium Conference Record, 2011
Ion beams exhibit a finite range and an inverted depth-dose profile (Bragg peak). These favourable physical properties allow superior tumour-dose conformality. However, they introduce sensitivity to range uncertainties. Although these uncertainties are typically taken into account in treatment planning, delivery of the intended treatment has to be ...
I. Rinaldi, S. Brons, O. Jakel, A. Mairani, R. Panse, B. Voss, K. Parodi   +6 more
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Hypofractionated proton and carbon ion beam radiotherapy for sacrococcygeal chordoma (ISAC): An open label, randomized, stratified, phase II trial.

Radiotherapy and Oncology
INTRODUCTION Sacrococcygeal chordomas have high recurrence rates and are challenging to treat. METHODS In this phase II prospective, randomized, stratified trial, the safety and feasibility of hypofractionated ion radiation therapy were investigated ...
K. Seidensaal, A. Froehlke, A. Lentz-Hommertgen, B. Lehner, A. Geisbuesch, J. Meis, J. Liermann, A. Kudak, K. Stein, M. Uhl, T. Tessonnier, A. Mairani, J. Debus, K. Herfarth   +13 more
semanticscholar   +1 more source

On the microdosimetric characterisation of the radiation quality of a carbon-ion beam and the effect of the target volume thickness

Physics in Medicine and Biology
Objective. Microdosimetry is gaining increasing interest in particle therapy. Thanks to the advancements in microdosimeter technologies and the increasing number of experimental studies carried out in hadron therapy frameworks, it is proving to be a ...
G. Parisi, G. Magrin, C. Verona, G. Verona-Rinati, S. Barna, C. Meouchi, Francesco Romano, Giuseppe Schettino   +7 more
semanticscholar   +1 more source

Experimental characterization of lateral profiles of scanned proton and carbon ion pencil beams for improved beam models in ion therapy treatment planning

Physics in Medicine and Biology, 2011
Scanned ion pencil beams carry a low-dose envelope which can extend up to several centimeters from the individual beam central axis. Depending on the energy and species of the beam, this halo consists mainly of secondary particles produced by nuclear interactions in the target or of particles undergoing multiple Coulomb scattering in the beam line ...
J, Schwaab, S, Brons, J, Fieres, K, Parodi   +3 more
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