Results 1 to 10 of about 774,901 (354)

One-carbon metabolism in cancer [PDF]

British Journal of Cancer, 2017
Cells require one-carbon units for nucleotide synthesis, methylation and reductive metabolism, and these pathways support the high proliferative rate of cancer cells.
AJ MacFarlane, Alice C Newman, AS Tibbetts, B Chaneton, BC Blount, C Commisso, CA Lewis, CF Labuschagne, CF Woeller, D Hanahan, D Hanahan, D Kim, DD Anderson, E Currie, E Mullarky, F Daidone, F Kottakis, G Kikuchi, GM DeNicola, Gregory S. Ducker, GS Ducker, J Liu, J Meiser, J Ye, Jason W. Locasale, JJ Kamphorst, JW Locasale, K Snell, K Snell, K Snell, Katherine R. Mattaini, L Galluzzi, M Goulian, M Jain, M Kulis, Mahya Mehrmohamadi, ME Pacold, Ming Yang, MJ Osborn, ML Rose, ML Rose, OD Maddocks, OD Maddocks, Oliver D K Maddocks, Oliver D. K. Maddocks, PM Ueland, R Possemato, S Farber, S Kit, S Pollari, SJ Mentch, Swetha Bolusani, T Shlomi, WC Zhang, Y Fu, Z Ser   +55 more
core   +5 more sources

Permafrost thawing and carbon metabolism [PDF]

Nature Reviews Microbiology, 2018
Three studies provide insights into the microbial lineages involved in carbon processing in thawing permafrost, the role of viruses in soil carbon cycling, and the pattern, extent and scientific implications of sampling bias in environmental field research across the Arctic.
Andrea Du Toit
openalex   +3 more sources

Wetland restoration suppresses microbial carbon metabolism by altering keystone species interactions [PDF]

Frontiers in Microbiology
Soil bacteria play a pivotal role in regulating multifaceted functions of terrestrial ecosystems. Unraveling the succession of bacterial communities and the feedback mechanism on soil organic carbon (SOC) dynamics help embed the ecology of microbiome ...
Huijie Zheng, Huijie Zheng, Deyan Liu, Ye Li, Zengming Chen, Junjie Li, Junjie Li, Yanhong Dong, Yanhong Dong, Cong Yang, Cong Yang, Yuncai Miao, Junji Yuan, Weixin Ding, Weixin Ding   +14 more
doaj   +2 more sources

Bringing carbon to life via one-carbon metabolism. [PDF]

Trends Biotechnol
One-carbon (C1) compounds found in greenhouse gases and industrial waste streams are underutilized carbon and energy sources. While various biological and chemical means exist for converting C1 substrates into multicarbon products, major challenges of C1 conversion lie in creating net value. Here, we review metabolic strategies to utilize carbon across
O'Keeffe S, Garcia L, Chen Y, Law RC, Liu C, Park JO.   +5 more
europepmc   +3 more sources

Genetic Interaction Analysis Reveals that Cryptococcus neoformans Utilizes Multiple Acetyl-CoA-Generating Pathways during Infection

mBio, 2022
Cryptococcus neoformans is an important human fungal pathogen for which the external environment is its primary niche. Previous work has shown that two nonessential acetyl-CoA metabolism enzymes, ATP-citrate lyase (ACL1) and acetyl-CoA synthetase (ACS1),
Katy M. Alden, Andrew J. Jezewski, Sarah R. Beattie, David Fox, Damian J. Krysan   +4 more
doaj   +1 more source

Estimation of Carbon Metabolism in Saccharomyces cerevisiae Acclimatized to Glycerol Assimilation with Quantitative PCR

Microorganisms, 2022
Saccharomyces cerevisiae has the potential to produce value-added chemicals; however, this strain is restricted by using glycerol as a carbon source. Although acclimatization of S.
Akihito Nakanishi, Kuan Zhang, Riri Matsumoto, Naotaka Yamamoto   +3 more
doaj   +1 more source

The Pleiotropic Effects of Carbohydrate-Mediated Growth Rate Modifications in Bifidobacterium longum NCC 2705

Microorganisms, 2023
Bifidobacteria are saccharolytic bacteria that are able to metabolize a relatively large range of carbohydrates through their unique central carbon metabolism known as the “bifid-shunt”.
Stéphane Duboux, Solenn Pruvost, Christopher Joyce, Biljana Bogicevic, Jeroen André Muller, Annick Mercenier, Michiel Kleerebezem   +6 more
doaj   +1 more source

Genome-Wide Analysis of Invertase Gene Family, and Expression Profiling under Abiotic Stress Conditions in Potato

Biology, 2022
The potato is one of the most important and valuable crops in terms of consumption worldwide. However, abiotic stressors are the critical delimiters for the growth and productivity of potato.
Asad Abbas, Adnan Noor Shah, Anis Ali Shah, Muhammad Azhar Nadeem, Ahmad Alsaleh, Talha Javed, Saqer S. Alotaibi, Nader R. Abdelsalam   +7 more
doaj   +1 more source

Transcriptome Analysis of Two Near-Isogenic Lines with Different NUE under Normal Nitrogen Conditions in Wheat

Biology, 2021
Nitrogen (N) is an essential nutrient element for crop productivity. Unfortunately, the nitrogen use efficiency (NUE) of crop plants gradually decreases with the increase of the N application rate.
Xinbo Zhang, Fujian Li, Yonggang Ding, Quan Ma, Yuan Yi, Min Zhu, Jinfeng Ding, Chunyan Li, Wenshan Guo, Xinkai Zhu   +9 more
doaj   +1 more source

Mechanisms Behind the Indirect Impact of Metabolic Regulators on Virulence Factor Production in Staphylococcus aureus

Microbiology Spectrum, 2022
Staphylococcus aureus is a human skin pathogen capable of causing invasive infections in many tissues in the human body. The host of virulence factors, such as toxins and proteases, available to S.
Amelia C. Stephens, Lance R. Thurlow, Anthony R. Richardson   +2 more
doaj   +1 more source