Results 31 to 40 of about 2,805,916 (243)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Hot deformation behavior and microstructural evolution of high-carbon high-strength low alloy steel

Journal of Materials Research and Technology
This study investigates the hot deformation behavior, microstructural evolution, and processing map of a high-carbon high-strength low alloy steel subjected to hot compression tests in the temperature range of 850 °C–1150 °C and strain rates from 0.01 s ...
Guoyang Li, Wei Long, Xinning Yu, Guilin Wu, Wenxiong Chen, Qi Jiang, Chaolei Zhang, Honghui Wu, Junheng Gao, Haitao Zhao, Shuize Wang, Xinping Mao   +11 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Crystallographic characteristics of acicular ferrite nucleated on inclusions in a HSLA steel

Journal of Materials Research and Technology
Acicular ferrite (AF) has been regarded as the optimal microstructure in steel welds and heat affect zones (HAZs), because of its superior combination of strength and toughness.
Haitao Zhao, Junheng Gao, Guilin Wu, Honghui Wu, Chaolei Zhang, Yuhe Huang, Yang Luo, Xiaoqian Yang, Shuize Wang   +8 more
doaj   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

Al–Si alloyed uncoated hot stamping steels for enhanced oxidation resistance

Journal of Materials Research and Technology
Hot stamping steels are extensively used in the production of lightweight automobile bodies, which are crucial for reducing carbon emissions. Although significant advancements have been made in the development of Si–Cr alloyed uncoated hot stamping ...
Zhaoqi Song, Kaixun Wang, Haitao Zhao, Long Ma, Junheng Gao, Honghui Wu, Yuhe Huang, Chaolei Zhang, Jun Lu, Shuize Wang, Xinping Mao   +10 more
doaj   +1 more source

Test and Detection of Antifreezing and Anticorrosion Performance of Carbon Nanofiber Bridge Concrete

International Journal of Analytical Chemistry, 2022
In order to solve the problems of carbon nanotubes, steel fibers, and carbon nanotubes + steel fibers on the compressive strength and impact resistance of concrete, the author proposes a test method for the frost resistance and corrosion resistance of ...
Huining Yang, Dan Wang, Huai Yu
doaj   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Microstructure evolution of austenite-to-martensite transformation in low-alloy steel via thermodynamically assisted phase-field method

Journal of Materials Research and Technology
The austenite-to-martensite phase transformation plays a crucial part in the microstructure evolution of steel, with the morphology and grain size of martensite being key factors that influence the mechanical properties. This study explores the influence
Kaiyang Wang, Zhihao Tian, Hong-Hui Wu, Jiaming Zhu, Shuize Wang, Guilin Wu, Junheng Gao, Haitao Zhao, Chaolei Zhang, Xinping Mao   +9 more
doaj   +1 more source

The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort

Arthritis Care &Research, EarlyView.
Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo, Ashish P. Balar, Aidan K. Strother, Subhash Kulkarni, Michael Hughes, Brian Skaug, Maureen D. Mayes, Shervin Assassi, Ali Y. Ayla, Zsuzsanna H. McMahan   +9 more
wiley   +1 more source