Results 241 to 250 of about 3,084,728 (307)

Van der Waals Gap‐Confined Molecular Engineering of MoS2 for Selectivity‐Enhanced and Humidity‐Tolerant Gas Sensing

open access: yesAdvanced Science, EarlyView.
Molecular confinement within van der Waals gaps of MoS2 is established as a powerful design strategy for selective and stable chemical sensing. Ethanol‐confined films simultaneously tune electronic doping, surface wettability, and sulfur vacancy configurations, suppressing water interference while enhancing NO2 adsorption.
Jae Hyung Shim   +12 more
wiley   +1 more source

Receptor‐Triggered Peptide Self‐Assembly Enables Multivalent Recruitment of Endogenous Antibodies for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Receptor‐triggered supramolecular self‐assembly converts monovalent antibody‐recruiting molecules into multivalent platforms directly on cancer cell membranes. The resulting fibrillar assemblies present clustered haptens that efficiently recruit endogenous antibodies, enabling selective complement‐mediated immune killing of EGFR‐positive cancer cells ...
Yihui Wang   +6 more
wiley   +1 more source

Mitochondrial Protection and Neural Repair via ROS‐Responsive Biomimetic Nanoparticles in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
A ROS‐responsive biomimetic nanoparticle platform co‐delivers DIDS and Mdivi‐1 to protect mitochondria and promote neural repair after intracerebral hemorrhage. By targeting LPAR1/VDAC1‐related mitochondrial dysfunction, the nanotherapy reduces oxidative injury, neuronal apoptosis, and blood‐brain barrier disruption, improving neurological recovery and
Ling Gao   +7 more
wiley   +1 more source

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

open access: yesAdvanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang   +4 more
wiley   +1 more source

Protonation Modification of Commercial OPBI as Binders Toward High‐Performance High‐Temperature PEM Fuel Cells

open access: yesAdvanced Science, EarlyView.
Commercial OPBI binders is regulated via a facile formic‐acid protonation strategy without disrupting the polymer backbone. Protonation introduces positively charged benzimidazole sites, inducing interchain electrostatic repulsion that loosens chain packing, enlarges intermolecular spacing, and promotes uniform binder dispersion over catalyst surfaces.
Jinzhen Huang   +5 more
wiley   +1 more source

A ROS‐Responsive and Mucoadhesive Thermosensitive Hydrogel Encapsulated with Mizoribine for Synergistic Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
The ROS‐responsive in situ thermosensitive MZR@SPPP hydrogel system enables dual‐stage drug loading and sustained ocular delivery. Upon administration, it gelates at ocular surface temperature, enhancing ocular adhesion. By scavenging free radicals, restoring NRF2‐mediated antioxidant defense and mitochondrial homeostasis, and suppressing inflammatory ...
Danyi Qin   +13 more
wiley   +1 more source

Determination of Gene‐Level Fitness Contributions Across the Mucin‐Utilization Network of Bacteroides thetaiotaomicron

open access: yesAdvanced Science, EarlyView.
Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim   +5 more
wiley   +1 more source

Nanoscale Buried Interface Control in Silicone Hydrogels Enables a Biointerface Engineering Platform

open access: yesAdvanced Science, EarlyView.
A hydrophilic coating with controllable nanoscale thickness is applied to commercial silicone hydrogel contact lenses. By combining comprehensive multi‐modal three‐dimensional characterization with an advanced algorithm, the thickness and chemical information of these multilayered structures are resolved.
Po‐Hsiang Chen   +5 more
wiley   +1 more source

Molecular Electrocatalysis Coupled With a Palladium Membrane Reactor Affords Selective Nitrogen Reduction

open access: yesAdvanced Science, EarlyView.
A palladium membrane reactor delivers active hydrogen to homogeneous nickel terpyridine catalysts, which then selectively hydrogenate dinitrogen to ammonia. ABSTRACT Ammonia production is a cornerstone of modern industry and society, yet the conventional Haber–Bosch process accounts for nearly 2% of the global CO2 emissions. A promising and potentially
Morgan McKee   +11 more
wiley   +1 more source

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