Protective Effect and Mechanism of Rosiglitazone in α-amanitin-induced Hepatotoxicity Via Activation of PPAR-γ/Nrf2 Signaling Pathway. [PDF]
J Biochem Mol ToxicolABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Lai F +8 more
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Morphology of mitochondria and cell respiration,pt.1. [PDF]
, 1960 To reveal the mechanism of liver damage by taking CCl4 the author observed the liver tissues from rats at 1.5, 5, 6, 10, 17, 20, and 22 hours after the CCl4 administration, both by light microscope and electron-microscope. 1. Light microscope observation
Haba, Kyoichi
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An electron microscope study of liver cell in carbon tetrachloride intoxication, significance of "opaque area" [PDF]
, 1961 Electron microscope study on the rat liver cells of carbon tetrachloride poisoning has been reported. Observations have been made on the osmic fixed tissue sections obtained from the liver at early stages of poisoning, 5 to 22 hours after carbon ...
Haba, Kyoichi, Seno, Satimaru
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Studies on hepatotoxicity induced by chlorinated hydrocarbons. Lipid and ATP metabolisms in the liver of mice exposed to 1,1,2,2-tetrachloroethane [PDF]
, 1969 With a constant gas-exposure chamber newly devised, the author had Cb mice (females weighing 16.0 ± 1.5 g) inhale 600 ppm (in average) of 1, 1, 2, 2-tetrachloroethane for 3 hours.
Tomokuni, Katsumaro
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Vergleich dreier Ringversuche zur radioimmunologischen Thyrotropin-Bestimmung nach dem "Münchner Modell" [PDF]
, 1983 Peer ...
Habermann, J. +5 more
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Toxics, 2018 Carbon tetrachloride (CCl4) is an efficient but highly toxic solvent, used in households and commercially in the industry under regulatory surveillance to ensure safety at the working place and to protect the workers’ health.
Rolf Teschke
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Enzymatic Studies of Glucuronide Formation in Impaired Liver III. Effects of Carbon Tetrachloride and Ectromelia Virus Infection on Liver Glucuronide Formation in Mouse [PDF]
, 1962 Glucuronide formations by mouse liver homogenate in several liver impairments were studied by using 4-methyl umbelliferone as a glucuronide receptor. The results were as follows : 1.
Taketa, Kazuhisa
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Studies on the portein synthesis in poisoning,1. [PDF]
, 1961 The incorporation of C14-2-glycine into the subcellular fractions of liver, kidney and serum proteins was observed in mice receiving CCl4 injections.
Ogata, Masana
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Journal of Lipid Research, 1971 Liver microsomal lipid peroxidation has been observed in fatal human CCl4 poisoning, in rats with fatty livers induced by CCl4 or by yellow phosphorus, and in mice poisoned with 1,1,2,2-tetrachloroethane.
S. Srinivasan, Richard O. Recknagel
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Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics [PDF]
, 2012 Introduction: In order to assess the significance of drug levels measured in intensive care medicine, clinical and forensic toxicology, as well as for therapeutic drug monitoring, it is essential that a comprehensive collection of data is readily ...
Andresen, Hilke +3 more
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