Protective Effect and Mechanism of Rosiglitazone in α-amanitin-induced Hepatotoxicity Via Activation of PPAR-γ/Nrf2 Signaling Pathway. [PDF]
J Biochem Mol ToxicolABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Lai F +8 more
europepmc +2 more sources
Global, regional, and national mortality due to unintentional carbon monoxide poisoning, 2000-2021: results from the Global Burden of Disease Study 2021 [PDF]
, 2023 BACKGROUND: Unintentional carbon monoxide poisoning is a largely preventable cause of death that has received insufficient attention. We aimed to conduct a comprehensive global analysis of the demographic, temporal, and geographical patterns of fatal ...
GBD 2021 Carbon Monoxide Poisoning Collaborators, +1 more
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The late effects of carbon monoxide poisoning [PDF]
, 2023 Carbon monoxide is a highly toxic gas for humans, which is formed as a result of the incomplete combustion of carbon-based fuels. It is a difficult gas to detect due to its non-irritant and high diffusion capacity.
Sultanoğlu, H. +2 more
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Diagnostic methods for carbon monoxide poisoning [PDF]
, 2023 The diagnosis of Carbon Monoxide (CO) poisoning consists of three elements: symptoms associated with carbon monoxide poisoning, exposure to CO, and an increase in COHb levels.
Akdur, Gökhan +2 more
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An electron microscope study of liver cell in carbon tetrachloride intoxication, significance of "opaque area" [PDF]
, 1961 Electron microscope study on the rat liver cells of carbon tetrachloride poisoning has been reported. Observations have been made on the osmic fixed tissue sections obtained from the liver at early stages of poisoning, 5 to 22 hours after carbon ...
Seno, Satimaru, Haba, Kyoichi
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Studies on hepatotoxicity induced by chlorinated hydrocarbons. Lipid and ATP metabolisms in the liver of mice exposed to 1,1,2,2-tetrachloroethane [PDF]
, 1969 With a constant gas-exposure chamber newly devised, the author had Cb mice (females weighing 16.0 ± 1.5 g) inhale 600 ppm (in average) of 1, 1, 2, 2-tetrachloroethane for 3 hours.
Tomokuni, Katsumaro
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Morphology of mitochondria and cell respiration,pt.1. [PDF]
, 1960 To reveal the mechanism of liver damage by taking CCl4 the author observed the liver tissues from rats at 1.5, 5, 6, 10, 17, 20, and 22 hours after the CCl4 administration, both by light microscope and electron-microscope. 1. Light microscope observation
Haba, Kyoichi
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Carbon Monoxide Poisoning: Saving Lives, Advancing Treatment [PDF]
, 2017 Carbon monoxide (CO) poisoning is a serious public health issue. In England and Wales alone, every year some 4,000 attendances to emergency departments (EDs) are the result of accidental CO poisoning.
Baroness Finlay of Llandaff, I +17 more
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Journal of Lipid Research, 1971 Liver microsomal lipid peroxidation has been observed in fatal human CCl4 poisoning, in rats with fatty livers induced by CCl4 or by yellow phosphorus, and in mice poisoned with 1,1,2,2-tetrachloroethane.
S. Srinivasan, Richard O. Recknagel
doaj +1 more source
Regulatory Mechanisms in Biosystems, 2016 This article presents the results of research into the influence of the complex liposomal preparation Butaintervit on protein synthesis function in the livers of rats under the influence of carbon tetrachloride poisoning.
M. I. Hariv, B. V. Gutyj
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