Results 51 to 60 of about 58,487 (222)

Keap1 Deletion Rescues Cell Death Associated With Gpx4 Loss in Hepatocytes During Acute Liver Injury

open access: yesLiver International, Volume 45, Issue 9, September 2025.
ABSTRACT Background & Aims Acute liver failure (ALF) is a life‐threatening condition with limited treatment options beyond liver transplantation in non‐acetaminophen cases. The extensive loss of liver function results from severe hepatocyte death, where elevated reactive oxygen species (ROS) play a significant role.
Leticia Colyn   +10 more
wiley   +1 more source

Functional, Nutraceutical and Health Endorsing Perspectives of Saffron

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Saffron is generally regarded as safe for human consumption in moderate quantities, its potential adverse effects at higher doses require careful consideration. This review presents a balanced perspective on saffron's medicinal potential and its safe usage, making it a valuable resource for researchers and healthcare professionals.
Tabussam Tufail   +4 more
wiley   +1 more source

Hepatoprotective effect of Descurainia sophia seed extract against paracetamol-induced oxidative stress and hepatic damage in mice [PDF]

open access: yes, 2018
Introduction: In this study, we aimed to evaluate the protective effects of Descurainia sophia seed extract on paracetamol-induced oxidative stress and acute liver injury in mice. Methods: Sixty male Swiss albino mice were divided into 6 groups, group I:
Faed Maleki, Firouz   +3 more
core   +2 more sources

Exploring the Potential Role of Quercetin Dihydrate Against Carbon Tetrachloride Induced Oxidative Stress in Mice: A Randomized Control Trial

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
In conclusion, by improving the oxidative stress markers, Quercetin Dihydrate exerted significant protection and antioxidant activities against carbon tetrachloride‐induced oxidative stress. ABSTRACT This study investigated the protective efficacy of Quercetin Dihydrate against carbon tetrachloride‐(CCl4) induced oxidative stress using an animal model.
Farzeen Asghar   +10 more
wiley   +1 more source

Expression of hepatocyte growth factor and its receptor c-met, correlates with severity of pathological injury in experimental alcoholic liver disease. [PDF]

open access: yes, 2005
Expression of hepatocyte growth factor (HGF) and its receptor, c-met is up-regulated in various forms of liver injury. This study evaluated the relationship between HGF and c-met expression and pathological changes in experimental alcoholic liver disease.
Fogt, Franz   +5 more
core   +2 more sources

Nephroprotective Effects of Fraxinus Hookeri Wenz. Against Renal Toxicity and DNA Oxidative Damages Induced by CCl4 in Rats

open access: yesChemistryOpen, Volume 14, Issue 8, August 2025.
This study evaluates the nephroprotective potential of Fraxinus hookeri Wenz. (F. hookeri), a medicinal plant of the Oleaceae family, against CCl4‐induced oxidative stress. The findings demonstrate its ability to restore antioxidant defenses, renal function markers, and DNA integrity while reducing lipid peroxidation and histopathological damage.
Raheela Sarwar   +9 more
wiley   +1 more source

WIDE COMPLEX TACHYCARDIA AFTER CARBON TETRACHLORIDE POISONING

open access: yesJournal of the American College of Cardiology, 2023
Kutaiba Nazif   +3 more
semanticscholar   +1 more source

Hepatotprotective Natural Products [PDF]

open access: yes, 2003
Medicinal herbs are significant source of pharmaceutical drugs. Latest trends have shown increasing demand of phytodrugs and some medicinal herbs have proven hepatotprotective potential.
Malhotra, Samir, Singh, Amrit Pal
core   +1 more source

Drug Hepatotoxicity: Environmental Factors [PDF]

open access: yes, 2017
Drug-induced liver injury presents as various forms of acute and chronic liver disease. There is wide geographic variation in the most commonly implicated agents.
Chalasani, Naga P., Stine, Jonathan G.
core   +1 more source

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