Results 101 to 110 of about 718,980 (307)

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Stable prenucleation mineral clusters are liquid-like ionic polymers [PDF]

, 2011
Calcium carbonate is an abundant substance that can be created in several mineral forms by the reaction of dissolved carbon dioxide in water with calcium ions.
Quigley, David, Demichelis, Raffaella, Gebauer, Denis, Gale, Julian, Quigley, D., Raiteri, Paolo, Gale, Julian D., Gebauer, D.   +7 more
core   +1 more source

Study on Co-Calcination of Vanadium-Chromium Slag and Artificial Marble Waste Slag Followed by Acid Leaching for Separation of Vanadium and Chromium

Metals
This study addresses the challenge of achieving efficient separation of vanadium and chromium from vanadium–chromium slag (VCS) while simultaneously tackling issues related to artificial granite waste residue (AGWR), such as its substantial stockpiling ...
Xiaoxin Xuan, Guangyu Zhang, Yiqiu Wang, Jinwei Qu, Yang Chen   +4 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Three-dimensional carbonate reservoir geomodeling based on the digital outcrop model

Petroleum Exploration and Development, 2015
To better know the spatial distribution and architecture of carbonate reservoirs, three-dimensional carbonate reservoir geologic modeling based on the digital outcrop model (DOM) is proposed.
Zhanfeng QIAO, Anjiang SHEN, Jianfeng ZHENG, Shaoying CHANG, Yana CHEN   +4 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Geological modeling of excellent fracture-vug carbonate reservoirs: A case study of the Ordovician in the northern slope of Tazhong palaeouplift and the southern area of Tabei slope, Tarim Basin, NW China

Petroleum Exploration and Development, 2013
Based on the reservoir characteristics of individual wells, the combined main controlling factor of fracture-vug reservoir and reservoir space synthesized modeling was adopted to establish geological models for the Ordovician reservoirs in the northern ...
Xinfeng NI, Anjiang SHEN, Wenqing PAN, Ronghu ZHANG, Hongfeng YU, Yong DONG, Yongfeng ZHU, Chaofeng WANG   +7 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source