Results 81 to 90 of about 651,839 (318)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Marine carbonate sedimentation in volcanic settings

open access: yes, 2023
Carbonate sediments have been produced and deposited in areas of active volcanism since at least the Paleoarchean. Despite early recognition of a significant relationship between volcanism and marine carbonate systems, research in this field has been ...
Lokier, S.
core   +1 more source

Sedimentary and reservoir architectures of MB1-2 sub-member of Middle Cretaceous Mishrif Formation of Halfaya Oilfield in Iraq

open access: yesPetroleum Exploration and Development, 2020
Based on comprehensive analysis of core, cast thin section, logging and seismic data, the sedimentary and reservoir architectures of the MB1-2 sub-member of Mishrif Formation in Halfaya Oilfield, Iraq, are studied.
Wenju SUN   +7 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Mangarara Formation: exhumed remnants of a middle Miocene, temperate carbonate, submarine channel-fan system on the eastern margin of Taranaki Basin, New Zealand

open access: yes, 2009
The middle Miocene Mangarara Formation is a thin (1–60 m), laterally discontinuous unit of moderately to highly calcareous (40–90%) facies of sandy to pure limestone, bioclastic sandstone, and conglomerate that crops out in a few valleys in North ...
Peter J.J. Kamp   +7 more
core   +1 more source

Experimental and analytical investigations of non-skeletal carbonate production

open access: yes, 2022
The overriding aim of this research is concerned with understanding the chemical controls on carbonate sedimentation in naturally occurring highly alkaline systems that produce enigmatic mineral assemblages.
Roest-Ellis, Sascha
core   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

The skeletal carbonate contribution to mixed terrigenous-carbonate sediments on the temperate northeastern Northland continental shelf, New Zealand

open access: yes, 2012
The northeastern Northland continental shelf (NNCS) includes the coastal, shelf and uppermost slope seafloor out to depths of 210 m and over a distance of 150 km between North Cape and Ngurauru Bay slightly north of Whangarei. The nature of the surficial
Rogers, Danielle Claire
core  

The Nummulitique: carbonate deposition in a foreland basin setting; Eocene, French alps [PDF]

open access: yes, 1995
The Eocene Nummulitique (Lutetian to Priabonian) has been studied in the external chains of the French Alps in Haute Savoie and Haute Provence. The Nummulitique unconformably overlies the Mesozoic passive margin succession and represents the onset of ...
Sayer, Zoë Rebecca
core  

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