Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
The skeletal carbonate contribution to mixed terrigenous-carbonate sediments on the temperate northeastern Northland continental shelf, New Zealand [PDF]
The northeastern Northland continental shelf (NNCS) includes the coastal, shelf and uppermost slope seafloor out to depths of 210 m and over a distance of 150 km between North Cape and Ngurauru Bay slightly north of Whangarei. The nature of the surficial
Rogers, Danielle Claire
core
Evaluating the utility of B/Ca ratios in planktic foraminifera as a proxy for the carbonate system : a case study of Globigerinoides ruber [PDF]
This research was funded by NERC, Grant Number: NE/D00876X/2.B/Ca ratios in foraminifera have attracted considerable scientific attention as a proxy for past ocean carbonate system.
Prentice, K.C. +7 more
core +1 more source
To investigate the development laws and genesis of the Maokou Formation dolomite in the Fengdu-Shizhu area, we analyzed core, thin section, logging, and geochemical data, and obtained the following understandings: 1.
Fabo Xu +8 more
doaj +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
To address the challenges in studying the pore formation and evolution processes, and unclear preservation mechanisms of deep to ultra-deep carbonate rocks, a high-temperature and high-pressure visualization simulation experimental device was developed ...
Anping HU +6 more
doaj +1 more source
Indigenous microbial communities as catalysts for early marine cements: An in vitro study
Early marine cementation is a fundamental process for many characteristics of carbonates, like the stabilisation of steep slopes. The genesis of early cements is often attributed to physicochemical processes but there is evidence for microbial mediation.
Mara R. Diaz +2 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Petrogenesis of diachronous mixed siliciclastic-carbonate megafacies in the cool-water Oligocene Tikorangi Formation, Taranaki Basin, New Zealand [PDF]
The Oligocene (Whaingaroan-Waitakian) Tikorangi Formation is a totally subsurface, lithostratigraphically complex, mixed siliciclastic-limestone-rich sequence forming an important fracture reservoir within Taranaki Basin, New Zealand.
Nelson, Campbell S. +5 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source

