Results 51 to 60 of about 2,259,887 (303)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

A Study on the Sedimentary Environment and Facies Model of Triassic Carbonate Rocks in the Mangeshlak Basin

Applied Sciences
Based on drilling, core and seismic data, combined with the regional tectonic sedimentary evolution background, the sedimentary environment of the Triassic carbonate rocks in the Mangeshlak Basin was studied.
Fanyang Meng, Kaixun Zhang, Zhiping He, Miao Miao, Feng Wang   +4 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The skeletal carbonate contribution to mixed terrigenous-carbonate sediments on the temperate northeastern Northland continental shelf, New Zealand [PDF]

, 2012
The northeastern Northland continental shelf (NNCS) includes the coastal, shelf and uppermost slope seafloor out to depths of 210 m and over a distance of 150 km between North Cape and Ngurauru Bay slightly north of Whangarei. The nature of the surficial
Rogers, Danielle Claire
core  

Carbonate platform demise across the Triassic-Jurassic transition in the Qiangtang Basin, Tibetan Plateau

Frontiers in Marine Science
IntroductionCarbonate platforms are highly sensitive to environmental, climatic, and oceanographic changes. The demise of carbonate platform is often associated with perturbations in oceanic chemistry and/or sea level rise, which are also the modern ...
Yi Zou, Hengye Wei, Ahmed Mansour, Ahmed Mansour, Yue Wen, Xiugen Fu   +5 more
doaj   +1 more source

Geohistorical analysis of the northern part of the Pai-Khoi carbonate parautochthone in Late Devonian–Carboniferous

Литосфера, 2020
Research subject. This article focuses on the geological structure of the northern part of the Pai-Khoi carbonate parautochthone.Materials and methods. The study was based on the data obtained on the key sections of the North-Western Pai-Khoi.
D. A. Gruzdev, A. I. Gerasimova, A. V. Zhuravlev, Ya. A. Vevel   +3 more
doaj   +1 more source

Carbon dots: a novel platform for biomedical applications

Nanoscale Advances, 2022
Carbon dots are a class of carbon-based nanostructures known as zero-dimensional nanomaterials. They have received a great deal of attention due to their distinctive features, which includes optical properties, ease of passivation, simple synthetic route.
Mohammadreza Behi, Leila Gholami, Sina Naficy, Stefano Palomba, Fariba Dehghani   +4 more
openaire   +3 more sources

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Facies and sequence stratigraphy of the tamet formation (middle eocene), eastern sirte basin, Libya [PDF]

, 1995
The middle Eocene Tamet Formation on the eastern side of the Sirte Basin, is largely shallow-marine carbonate platform-to-basin transition formed along passive margin.
El Hassi, Aiyad Mohamed
core