Results 101 to 110 of about 70,075 (318)
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
p-Nitrophenyl carbonate promoted ring-opening reactions of DBU and DBN affording lactam carbamates
Beilstein Journal of Organic Chemistry, 2016 The amidine bases DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) and DBN (1,5-diazabicyclo[4.3.0]non-5-ene) display nucleophilic behaviour towards highly electrophilic p-nitrophenyl carbonate derivatives with ring opening of the bicyclic ring to form ...
Madhuri Vangala, Ganesh P Shinde
doaj +1 more source
Workshop: Oligo-Miocene shallow water carbonates: biogenic components and facies
, 2003 Workshop: Oligo-Miocene shallow water carbonates: biogenic components and ...
BASSI, Davide
core
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Examples of Paleokarst in Mesozoic Carbonate Formations in the Carpathian Foreland Area
EnergiesA paleokarst system developed in the Upper Jurassic–Lower Cretaceous carbonate complex has been recognized in the Carpathian Foreland area. Well logs testing and core data as well as an acoustic imager, a microresistivity scanner and six-arm dipmeter ...
Anna Łaba-Biel +7 more
doaj +1 more source
Czech Journal of Food Sciences, 2003 Formation of 3-chloropropane-1,2-diol (3-MCPD) was studied in model mixtures consisting of sodium chloride and either glycerol or various lipids (phospholipids, monoacylglycerols, diacylglycerols, triacylglycerols) derived mainly from palmitic and oleic ...
J. Velíšek +4 more
doaj +1 more source
NMR relaxation of neritic carbonates: An integrated petrophysical and petrographical approach
, 2011 International audienceA set of carbonate outcrop samples, covering a wide range of the sedimentary textures and depositional environments existing on carbonate systems, was studied through an integrated petrographical and petrophysical approach. With the
Vincent, Benoit +7 more
core +1 more source
Molybdenum isotopic composition of modern and Carboniferous carbonates [PDF]
, 2009 We investigate the redox-sensitive isotope system of molybdenum (Mo) in marine carbonates to evaluate their potential as archive of the Mo isotopic composition of coeval seawater.
Voegelin, Andrea R. +9 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose Air pollution has been linked to several neurological conditions, including stroke and neurodegenerative diseases. Evidence regarding its association with multiple sclerosis (MS) remains conflicting, limited by small sample sizes. Methods PubMed, Embase, Scopus, and Cochrane controlled register of trials (CENTRAL) were searched on ...
Ahmad A. Toubasi, Thuraya N. Al‐Sayegh
wiley +1 more source