Results 81 to 90 of about 86,603 (302)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Anais da Academia Brasileira de Ciências, 2009 The late Cambrian - late Tremadocian La Silla Formation is a carbonate unit of the eastern Precordillera in Argentina whose facies indicate a shallow platform environment. Until this moment, there were no studies that referred to the diagenetic evolution
Mariana M. Raviolo +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Trace elements in marine biogenic carbonates: analysis and application to past ocean chemistry
, 2008 Trace elements in marine biogenic carbonates may be used as proxies for past oceanchemistry provided that there is an established relationship between the trace elementproxy and a parameter of interest, this relationship is preserved within ...
Greaves, Mervyn John
core +1 more source
METODOLOGIA EXPERIMENTAL PARA REAÇÕES GÁS-LÍQUIDO
Química Nova, 2016 Although the gas-liquid reactions are employed in many industrial processes, this issue in the most of time is not included in the curriculum of Chemistry and Chemical Engineering courses.
Lilian C. Mello +2 more
doaj +1 more source
Proglacial sedimentation of late Wisconsin age in Miers Valley, Antarctica [PDF]
, 2013 Miers Valley is an ice free valley in the Koettlitz Region of Victoria Land, Antarctica. The eastern basin of this valley has extensive coverage of gypsum and laminated calcite overlying fine silts and sands, while Lake Miers occupies the western basin ...
Clayton-Greene, Jan Maree
core
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Pedogenic Carbonates and Radiocarbon Isotopes of Organic Carbon at Depth in the Russian Chernozem
Geosciences, 2018 Conversion of native grasslands to agricultural sites has resulted in remarkable changes in soil carbon at depth, but its impact on soil diagnostic horizons is unknown.
Elena A. Mikhailova +8 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Modélisation et analyse d’un milieu granulaire carbonaté à haute température
Revue des Énergies Renouvelables, 2010 La compréhension et la maîtrise des facteurs qui gouvernent le traitement thermique des milieux granulaires sont nécessaires dans plusieurs applications de l’industrie chimique et pharmaceutique.
M. El Ouardi
doaj