Results 71 to 80 of about 189,696 (282)

Cementation scenarios for New Zealand Cenozoic nontropical limestones [PDF]

, 1996
Cenozoic limestones are widely distributed in New Zealand, especially in the Oligocene-earliest Miocene in both islands, and the Pliocene-Pleistocene in North Island.
Hood, Steven D., Nelson, Campbell S.
core   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Fluid evolution in CM carbonaceous chondrites tracked through the oxygen isotopic compositions of carbonates [PDF]

, 2017
The oxygen isotopic compositions of calcite grains in four CM carbonaceous chondrites have been determined by NanoSIMS, and results reveal that aqueous solutions evolved in a similar manner between parent body regions with different intensities of ...
Alexander, Alexander, Barber, Benedix, Bland, Bonal, Bunch, Burbine, Clark, Clayton, Clayton, de Leuw, DuFresne, Emery, Fujiya, Fujiya, Guo, Hewins, Horita, Howard, I.A. Franchi, Jenniskens, Johnson, Kasuga, Lauretta, Lee, Lee, Lee, Lee, Lee, Lee, Lindgren, Lindgren, M.R. Lee, Marrocchi, McSween, McSween, N.A. Starkey, P. Lindgren, Palguta, Rubin, Rubin, Starkey, Tomeoka, Tyra, Tyra, Tyra, Velbel, Young, Young   +49 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

COMBINATION OF SALINE SOILS OF THE NORTHERN SLOPE OF THE ERGENI UPLAND AFTER IRRIGATION CESSATION

Бюллетень Почвенного института им. В.В. Докучаева, 2019
The soil cover and soil salinity of the field were studied and the results are given in the article, the explored fileld is located within the Chervlenoye irrigated area belonging to Svetloyarskaya irrigation system (south of the Volgograd region).
N. B. Khitrov, I. N. Gorokhova, E. I. Kravchenko   +2 more
doaj   +1 more source

The Lomagundi-Jatuli carbon isotopic event recorded in the marble of the Tandilia System basement, Río de la Plata Craton, Argentina [PDF]

, 2019
The “Lomagundi-Jatuli event” corresponds to the most important δ13C positive anomaly (≥5‰) globally reported in Palaeoproterozoic marine carbonates (between ∼2.30 and 2.06 Ga).
Ballivian Justiniano, Carlos Alberto, Cingolani, Carlos Alberto, Etcheverry, Ricardo Oscar, Lajoinie, Maria Florencia, Lanfranchini, Mabel Elena, Recio, C., Sial, A.N.   +6 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Quantitative characterization of the carbonate rock microstructure considering topological features: a case study from the Gaoshiti–Moxi block of the Sichuan Basin

Frontiers in Earth Science
The precise characterization of the rock microstructure is crucial for predicting the physical characteristics, flow behavior, and mechanical properties of rocks.
Huaimin Dong, Huaimin Dong, Bin Luo, Chenyue Dang, Shuang Xu, Feng Wang, Peng Chi   +6 more
doaj   +1 more source

Experimental Approach to the Direct Interaction Between the H2O-CO2 Atmosphere and the Crust on the Earliest Earth: Implications for the Early Evolution of Minerals and the Proto-Atmosphere

Frontiers in Earth Science, 2018
Batch experiments between solid materials including komatiite, peridotite and basalt with an H2O-CO2 atmosphere were performed at temperatures from 200°C to 500°C to simulate the interaction between the new rocky crust formed after the magma ocean stage ...
Xi-Luo Hao, Xi-Luo Hao, Xi-Luo Hao, Yi-Liang Li   +3 more
doaj   +1 more source