Results 41 to 50 of about 129,195 (289)

Survival Outcomes and Complications Among Canadian Children With Retinoblastoma: A Population‐Based Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Retinoblastoma (RB) is the most common pediatric ocular cancer, yet population‐based data on survival and risk factors remain limited. This study aimed to describe survival in a large national RB cohort and identify predictors of death and complications.
Samuel Sassine, Ofélie Trudeau‐Ferrin, Caroline Laverdière, Patrick Hamel, Rosanne Superstein, Bénédicte Koukoui, Carole Provost, Paul C. Nathan, Vijay Ramaswamy, Furqan Shaikh, Brenda Gallie, Ashwin Mallipatna, Stephanie Kletke, Helen Dimaras, Hallie Coltin   +14 more
wiley   +1 more source

Small cell glioblastoma: A glioblastoma subtype with an unexpected response [PDF]

Modern Medicine, 2019
Small cell glioblastoma is a subtype of glioblastoma, an uncommon, with poor prognosis. Due to its rarity, reports of molecular genetics and immunohistochemistry are required to understand the tumor behavior.
Ionela Bizu, Mihai Georgescu, Rodica Anghel   +2 more
doaj   +1 more source

Whole tumor RNA-sequencing and deconvolution reveal a clinically-prognostic PTEN/PI3K-regulated glioma transcriptional signature [PDF]

, 2017
The concept that solid tumors are maintained by a productive interplay between neoplastic and non-neoplastic elements has gained traction with the demonstration that stromal fibroblasts and immune system cells dictate cancer development and progression ...
Bush, Erin C, Gutmann, David H, Ma, Yu, Pan, Yuan, Sims, Peter A, Solga, Anne C, Toonen, Joseph A   +6 more
core   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Thymic squamous cell carcinoma in a cat.

Open Veterinary Journal, 2022
Background: The most common cranial mediastinal masses affecting dogs and cats include lymphoma and thymic epithelial tumours (TETs). In this report, a cat with a cranial mediastinal mass was diagnosed with a thymic carcinoma subtype squamous cell ...
Richard Chung Yi Looi
doaj   +1 more source

Stromal tumor-infiltrating lymphocytes and pathologic response to neoadjuvant chemotherapy with the addition of platinum and pembrolizumab in TNBC: a single-center real-world study

Breast Cancer Research
Background Immunochemotherapy with pembrolizumab has been integrated into clinical practice as part of the standard-of-care for non-metastatic triple-negative breast cancer (TNBC) with high risk.
Soong June Bae, Jee Hung Kim, Min Ji Kim, Yoonwon Kook, Seung Ho Baek, Jung Hyun Kim, Sohyun Moon, Seung Eun Lee, Joon Jeong, Yoon Jin Cha, Sung Gwe Ahn   +10 more
doaj   +1 more source

Intratumoral chemotherapy in an integumentary squamous cell carcinoma in a cockatiel (Nymphicus hollandicus) [PDF]

, 2018
An eight-year-old, female cockatiel (Nymphicus hollandicus) was presented with anorexia, lethargy, a mass at the lower side of the wing and discoloration of the feathers.
Antonissen, Gunther, Croubels, Siska, Ducatelle, Richard, Garmyn, An, Hellebuyck, Tom, Martel, An, Van de Maele, Isabel, Van Hecke, Naomi   +7 more
core  

New markers for human ovarian cancer that link platinum resistance to the cancer stem cell phenotype and define new therapeutic combinations and diagnostic tools [PDF]

, 2019
BACKGROUND: Ovarian cancer is the leading cause of gynecologic cancer-related death, due in part to a late diagnosis and a high rate of recurrence. Primary and acquired platinum resistance is related to a low response probability to subsequent lines of ...
Carnero Moya, Amancio, Domínguez Piñol, Julia, Espinosa Sánchez, Asunción, Felipe Abrio, Blanca, García Carrasco, Miguel, García Heredia, José Manuel, Muñoz Galván, Sandra, Navas Maldonado, Lola Eufemia, Otero Abiol, Daniel, Suarez Martínez, Elisa, Verdugo Sivianes, Eva María   +10 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Chemical inhibition of the heat shock response downregulates ERCC1 gene expression and shifts carboplatin-induced necrosis to apoptosis in TNBC cells

Trakya University Journal of Natural Sciences
Background: Triple-negative breast cancer (TNBC) is an aggressive cancer type associated with poor prognosis and limited therapeutic options. Due to the absence of targetable receptors, conventional chemotherapy remains the primary treatment approach ...
Beyza Reisoğlu, Mehmet Alper Arslan
doaj   +1 more source