Results 71 to 80 of about 129,195 (289)

Combination Antiemetic Therapy for Chemotherapy-Induced Nausea and Vomiting in Patients with NSCLC Receiving Carboplatin-Based Chemotherapy

Cancer Management and Research, 2022
Mototsugu Shimokawa,1,2,* Naoki Haratake,3,* Kazuki Takada,4 Gouji Toyokawa,5 Shinkichi Takamori,6 Fumitaka Mizuki,7 Tomoyoshi Takenaka,3 Toshinobu Hayashi8 1Department of Biostatistics, Graduate School of Medicine, Yamaguchi University ...
Shimokawa M, Haratake N, Takada K, Toyokawa G, Takamori S, Mizuki F, Takenaka T, Hayashi T   +7 more
doaj  

Long-term renal function and hypertension in adult survivors of childhood sarcoma [PDF]

, 2018
Aim: Little data is available on long-term renal impairment in survivors from childhood sarcoma. We investigated the prevalence of renal impairment and hypertension after very long-term follow-up in survivors who reached adulthood after treatment for ...
Andreoli, Gianmarco, Bonci, Enea, Celani, Camilla, Marrucci, Oriana, Pedetti, Valeria, Schiavetti, Amalia, Varrasso, Giulia   +6 more
core   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Single‐Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re‐Sensitizer Drugs in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu, Mengqin Yuan, Yini Shang, Jiahao Chen, Fei Hou, Lihong Wang, Wei Jiang   +6 more
wiley   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Еvaluation of ameliorative efficacy of carboplatin with pioglitazone through adiponectin augmentation by activating PPAR-γ in high-fat diet-induced ovarian cancer in mice

Macedonian Veterinary Review
Carboplatin is one of the preferred treatments for ovarian cancer. To improve the therapeutic effectiveness of carboplatin in ovarian cancer, the novel combination therapy of carboplatin with the peroxisome proliferator-activated receptor-gamma agonist ...
Sudhakar Pachiappan, Selva Preethi Samundi, Sumitha Pachiappan, Panneerselvam Theivendren, Parasuraman Pavadai, Sabarinath Chandrasekar, Gomathi Vengatachalam   +6 more
doaj   +1 more source

Combining Chemotherapy Agents and Autophagy Modulators for Enhanced Breast Cancer Cell Death [PDF]

Advanced Pharmaceutical Bulletin
Purpose: Autophagy, governed by genes with dual roles in cell death and survival, plays a crucial role in cancer persistence. Arsenic trioxide (ATO), carboplatin (CP), and cyclophosphamide (CY) are used to treat various cancers.
Soraya Moomivand, Mohsen Nikbakht, Ahmad Majd, Maryam Bikhof Torbati, Seyed Asadoullah Mousavi   +4 more
doaj   +1 more source

Phase i study of \u27dose-dense\u27 pemetrexed plus carboplatin/radiotherapy for locally advanced non-small cell lung carcinoma. [PDF]

, 2011
BACKGROUND: This phase I study investigates the feasibility of carboplatin plus dose-dense (q2-week) pemetrexed given concurrently with radiotherapy (XRT) for locally advanced and oligometastatic non-small cell lung cancer (NSCLC).
Axelrod, Rita, Curran, Walter J, Denittis, Albert, Gilman, Paul, Machtay, Mitchell, Meyer, Thomas, Shen, Xinglei, Treat, Joseph, Werner-Wasik, Maria   +8 more
core   +1 more source

MAP17 predicts sensitivity to platinum-based therapy, EGFR inhibitors and the proteasome inhibitor bortezomib in lung adenocarcinoma [PDF]

, 2018
Background The high incidence and mortality of lung tumours is a major health problem. Therefore, the identification both of biomarkers predicting efficacy for therapies in use and of novel efficacious therapeutic agents is crucial to increase patient ...
Carnero Moya, Amancio, Ferrer, Irene, García Heredia, José Manuel, Molina Pinelo, Sonia, Pérez, Marco, Quintanal Villalonga, Álvaro Diego   +5 more
core   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source