Results 161 to 170 of about 79,493 (196)

Purification and cDNA Cloning of UDP-d-Glucuronate Carboxy-lyase (UDP-d-xylose Synthase) from Pea Seedlings

Plant and Cell Physiology, 2002
Uridine diphospho-D-glucuronate carboxy-lyase (UDP-D-xylose synthase; EC 4.1.1.35), which catalyzes the conversion of UDP-D-glucuronate to UDP-D-xylose, was purified to apparent homogenity from pea (Pisum sativum L.) seedlings. The pH optimum for enzyme activity was around 5-6, and the activity was not affected by exogeneously supplied NAD+ and NADH ...
Masaru, Kobayashi, Hironobu, Nakagawa, Izumi, Suda, Isao, Miyagawa, Toru, Matoh   +4 more
openaire   +2 more sources

Investigations on the presence of porphyrinogen carboxy-lyase inhibitor in the liver of rats intoxicated with hexachlorobenzene

International Journal of Biochemistry, 1980
Abstract 1. 1. It has been reported that hexachlorobenzene (HCB) in vivo produces hepatic porphyrinogen carboxy-lyase (PCL) decrease and pentachlorophenol (PCP) is one of its metabolites. In order to investigate if such decrease is due to an enzyme inhibitor present in the porphyric livers, the effects of the following additions on the normal rat
M C, Rios de Molina, R, Wainstok de Calmanovici, L C, San Martin de Viale   +2 more
openaire   +2 more sources

L-Arginine carboxy-lyase of higher plants and its relation to potassium nutrition

Phytochemistry, 1963
Abstract On a fresh weight basis the mean agmatine content was found to be eight times as high, and the mean L -arginine carboxy-lyase (arginine decarboxylase) activity twice as high in leaves of potassium-deficient barley plants as in leaves of normal barley plants. A range of other plant species was also shown to accumulate agmatine and putrescine
openaire   +1 more source

Activity of L-Cysteinesulfinate Carboxy-lyase and Persulfurase in Livers of Rats Fed Different Levels of Sulfate and Cysteine

The Journal of Nutrition, 1976
Activity of L-cysteinesulfinate carboxy-lyase (CSC) and persulfurase was measured in livers of rats fed 15% casein diets supplemented with (1) 0.53% cysteine, (2) 0.40% cysteine, (3) 0.40% cysteine + 0.10% sulfate, (4) 0.42% sulfate, or (5) 0.42% sulfate + 0.40% cysteine. The diets were fed to adult rats for 1 week and to weanling rats for periods of 1
B A, Whittle, C H, Lee
openaire   +2 more sources

Biosynthesis of uridine diphosphate d-xylose V. UDP-d-glucuronate and UDP-d-galacturonate carboxy-lyase of Ampullariella digitata

Archives of Biochemistry and Biophysics, 1972
Abstract Partially purified sonic extract of Ampullariella digitata strain 399 converted UDPGlcUA or UDPGalUA to a mixture of UDPGalUA, UDPGlcUA, UDPXyl and UDPAra. However, the extract did not catalyze the reaction: UDPXyl ⇄ UDPAra. In the presence of unlabeled UDPXyl, UDP-[ 14 C]GlcUA yielded only UDP-[ 14 C]Xyl, and UDP-[ 14 C]GalUA yielded only
D F, Fan, D S, Feingold
openaire   +2 more sources

ACLY inhibition promotes tumour immunity and suppresses liver cancer

Nature
Immunosuppressive tumour microenvironments are common in cancers such as metabolic dysfunction-associated steatohepatitis (MASH)-driven hepatocellular carcinoma (HCC) (MASH-HCC)1, 2–3.
Jaya Gautam, Jianhan Wu, James Lally, Jamie D McNicol, Russta Fayyazi, Elham Ahmadi, D. Oniciu, Spencer Heaton, Roger S. Newton, S. Rehal, Dipankar Bhattacharya, F. Di Pastena, Binh Nguyen, Celina M. Valvano, Logan K. Townsend, S. Banskota, B. Batchuluun, Maria Joy Therese Jabile, Alice E Payne, Junfeng Lu, Eric M. Desjardins, Naoto Kubota, E. Tsakiridis, Bejal Mistry, Alex Aganostopoulos, Vanessa Houde, A. Dansercoer, K. Verschueren, S. Savvides, Joanne A. Hammill, Ksenia Bezverbnaya, Paola Muti, T. Tsakiridis, W. Dai, Lei Jiang, Y. Hoshida, Mark Larché, Jonathan L. Bramson, Scott L. Friedman, K. Verstraete, Dongdong Wang, Gregory R. Steinberg   +41 more
semanticscholar   +1 more source

Tetrapyrroles as substrates and inhibitors of porphyrinogen carboxy - lyase from rat liver.

Acta physiologica latino americana, 1978
Porphyrinogen carboxy-lyase is an enzyme of the haem pathway which catalyses the stepwise decarboxylation of porphyrinogens with different number of carboxyl groups. This enzyme has a low substrate specificity since at least eighteen porphyrinogens were proved to be decarboxylated by the enzyme.
L C, San Martín de Viale, A, Aragonés, J M, Tomio   +2 more
openaire   +1 more source

Does feeding of hexachlorobenzene promote structural changes in rat-liver porphyrinogen carboxy-lyase?

IARC scientific publications, 1987
This study aimed to determine whether drug treatment produced structural changes in porphyrinogen carboxy-lyase enzymatic protein, leading to altered properties. Rat-liver enzyme was obtained from normal animals and from those with hexachlorobenzene (HCB)-induced porphyria, and several of its properties were comparatively studied. The enzymes from both
M del C, Ríos de Molina, S C, Billi, L C, San Martín de Viale   +2 more
openaire   +1 more source

Oxaloacetate 4-carboxy-lyase from Pseudomanas ovalis Chester

Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects, 1964
A A, HORTON, H L, KORNBERG
openaire   +2 more sources

Screening for the ability of hexachlorobenzene metabolites to decrease rat liver porphyrinogen carboxy-lyase.

Research communications in chemical pathology and pharmacology, 1986
In order to examine inhibitory effects of hexachlorobenzene metabolites on the hepatic porphyrinogen carboxylyase activity, rat liver cytosol was incubated with uroporphyrinogen III and chlorinated phenols, thiophenols, thioanisoles and benzenes. Then, the occurrence of hepta-, hexa-, penta- and tetracarboxyporphyrinogen = coproporphyrinogen (measured ...
S C, Billi, G, Koss, L C, San Martin de Viale   +2 more
openaire   +1 more source