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Hexachlorobenzene (HCB) residues in fish
Bulletin of Environmental Contamination and Toxicology, 1974Analysis of fish collected by the U.S. Fish and Wildlife Service for the fall 1970 National Pesticide Monitoring Program detected the presence of a compound eluting with, and subsequently identified incorrectly as B-benzenehexachloride. This compound was frequently observed when Florisil cleanup was used in the analysis of organochlorine residues in ...
J L, Johnson, D L, Stalling, J W, Hogan
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Hexachlorobenzene distribution in tissues of swine
Toxicology and Applied Pharmacology, 1979Abstract Purified hexachlorobenzene (HCB) was administered to third-litter sows at dietary concentrations of 0, 1, or 20 ppm throughout gestation and nursing. Swine receiving 1 ppm were not adversely affected and residue concentrations in tissues other than fat and bone marrow remained at or below the dietary concentration.
L G, Hansen +3 more
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Perinatal hexachlorobenzene toxicity in the mink
Environmental Research, 1983Adult female standard dark mink were exposed to hexachlorobenzene (HCB) at concentrations of 0, 1, and 5 ppm in the feed and bred with males on the same treatments. Female offspring were allowed to mature to 16-17 weeks and killed. At 16-17 weeks of age, HCB had no effect on body weights or liver weights.
G F, Rush +6 more
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Hexachlorobenzene (HCB): A review
Environmental Research, 1979Current knowledge about hexachlorobenzene (HCB) is reviewed. HCB is not a naturally occurring compound and is known to accumulate in both terrestrial and marine animals. The toxicity to human beings of long-term low level exposure to HCB is discussed. The occurrence of HCB in humans, food, wild mammals, birds, fish, and soil is described.
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Effect of hexadecane on the pharmacokinetics of hexachlorobenzene
Toxicology and Applied Pharmacology, 1984Sixty rats were divided into two groups; one group received normal Rat Chow and the other the same feed supplemented with 5% hexadecane. Twenty-four hours later, the rats were injected iv with 1.0 mg/kg [14C]hexachlorobenzene (HCB). For 1 month after dosing, the activity of 14C was determined in various tissues and in serum at predetermined intervals ...
E, Scheufler, K, Rozman
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2000
Abstract Hexachlorobenzene (HCB), formerly used as a seed fungicide, is a persistent pollutant that accumulates in the environment, in animals, and in humans. HCB disrupts the porphyrinheme biosynthetic pathway, resulting in porphyria attended by photosensitivity, skin lesions, and liver pathology.
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Abstract Hexachlorobenzene (HCB), formerly used as a seed fungicide, is a persistent pollutant that accumulates in the environment, in animals, and in humans. HCB disrupts the porphyrinheme biosynthetic pathway, resulting in porphyria attended by photosensitivity, skin lesions, and liver pathology.
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Subacute toxicity of hexachlorobenzene in the rat
Toxicology and Applied Pharmacology, 1977Abstract Male and female rats of the Charles River strain were fed a commercial diet supplemented with 5% corn oil. Hexachlorobenzene (HCB) was added to the corn oil to give 0, 0.5, 2, 8, or 32 mg of HCB/day/kg/body weight. Subgroups of four rats of each sex were killed at 3, 6, 9, 12, and 15 weeks of feeding.
T, Kuiper-Goodman +4 more
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Photolysis of hexachlorobenzene
Journal of Agricultural and Food Chemistry, 1976J R, Plimmer, U I, Klingebiel
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Oncogenicity of hexachlorobenzene.
IARC scientific publications, 1987Subchronic and chronic toxicities of hexachlorobenzene (HCB) were studied in both sexes of Swiss mice, Syrian golden hamsters and Sprague-Dawley rats, at dietary dosages of 0, 100 and 200 ppm (mice), and 0, 200 and 400 ppm (hamsters and rats) for 90 days. At day 91, 25/50 animals in each of 18 groups were killed for histology studies.
E, Ertürk +6 more
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Biotransformation of the fungicides hexachlorobenzene and pentachloronitrobenzene
Xenobiotica, 1981This overview of the metabolism of the fungicides hexachlorobenzene (HCB) and pentachloronitrobenzene (PCNB) indicates similarities in their pathways of biotransformation. Several metabolites of HCB and PCNB, such as chlorinated benzenes, the mercapturic acid, thiophenols, thioanisoles and phenols are identical.
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