Results 161 to 170 of about 14,952 (193)
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Canadian Journal of Biochemistry, 1975
Chicken, sheep, and horse liver carboxylesterases have been purified by procedures involving ammonium sulfate fractionation, ion-exchange chromatography and gel filtration on Sephadex. The actual yields of the procedures described were as follows: chicken, 1 g from 2 kg of liver powder (chloroform–acetone); sheep, 200 mg from 400 g of powder ...
P A, Inkerman +5 more
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Chicken, sheep, and horse liver carboxylesterases have been purified by procedures involving ammonium sulfate fractionation, ion-exchange chromatography and gel filtration on Sephadex. The actual yields of the procedures described were as follows: chicken, 1 g from 2 kg of liver powder (chloroform–acetone); sheep, 200 mg from 400 g of powder ...
P A, Inkerman +5 more
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Drug Metabolism and Disposition, 2011
Human carboxylesterase (CES) 1 and CES2 are members of the serine hydrolase superfamily, and both exhibit broad substrate specificity and are involved in xenobiotic and endobiotic metabolism. Although expression of CES1 and CES2 occurs in several organs, their expression in liver and small intestine is predominantly attributed to CES1 and CES2 ...
Jie, Wang +4 more
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Human carboxylesterase (CES) 1 and CES2 are members of the serine hydrolase superfamily, and both exhibit broad substrate specificity and are involved in xenobiotic and endobiotic metabolism. Although expression of CES1 and CES2 occurs in several organs, their expression in liver and small intestine is predominantly attributed to CES1 and CES2 ...
Jie, Wang +4 more
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Biochemical and Biophysical Research Communications, 1975
During the final stage of purification of pig liver carboxylesterase on CM-Sephadex, several enzyme activities are present in addition to the pig liver carboxylesterase reported from this laboratory (Horgan et al., 1969a). Variation in substrate specificity and specific activity of the material isolated from CM-Sephadex has been analysed with four ...
Hamilton S.E. +3 more
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During the final stage of purification of pig liver carboxylesterase on CM-Sephadex, several enzyme activities are present in addition to the pig liver carboxylesterase reported from this laboratory (Horgan et al., 1969a). Variation in substrate specificity and specific activity of the material isolated from CM-Sephadex has been analysed with four ...
Hamilton S.E. +3 more
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Heterogeneity of carboxylesterases in rat liver cells
Biochemical Pharmacology, 1992Rat liver cells were separated into parenchymal cells (PC), Kupffer cells (KC) and endothelial cells (EC). The distribution of carboxylesterases (EC 3.1.1.1) between these cell types was investigated by PAGE and chromatogenic substrate staining, and compared with the results for total liver preparation and individual isoenzymes isolated by ...
R, Gaustad, T, Berg, F, Fonnum
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[45] Carboxylesterases-amidases
1981Publisher Summary This chapter presents the simultaneous purification of five of the most prominent rat liver carboxylesterases-amidases. All of these enzymes are found in microsomal fraction. As a side product of the procedure described in the chapter , a dipeptidyl aminopeptidase is obtained that also belongs to the group of serine hydrolases.
Eberhard Heymann, Rolf Mentlein
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Carboxylesterases (EC 3.1.1). Dissociation of ox liver carboxylesterase
Biochemistry, 1969M T, Runnegar, E C, Webb, B, Zerner
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Carboxylesterases (EC 3.1.1). Purification and titration of ox liver carboxylesterase
Biochemistry, 1969Runnegar M.T.C. +3 more
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Studies on liver carboxylesterases
2017Procedures for the purification of horse and shark liver carbostyl.esterases are reported together with a modified procedure for the purification of sheep liver carboxylesterase. In the procedure for the horse enzyme, the starting material is an acetone powder, whereas for the other two enzymes, it is a chloroform-acetone powder.
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Microsomal Amidases and Carboxylesterases
1994Deacylation is an important biological reaction which affects the efficacy and toxicity of chemotherapeutic amides and the carcinogenicity of aryl and heterocyclic amides. It is catalyzed by amidases, a group of nonspecific hydrolytic enzymes which are present mainly in microsomes.
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