Results 241 to 250 of about 444,091 (356)

6-Isoprenylindole-3-carboxylic Acid with an Anti-Melanogenic Activity from a Marine-Derived <i>Streptomyces</i> sp. APA-053. [PDF]

Mar Drugs
Kim M, Lee EY, Shin GE, Chin J, An H, Nam SJ, Lim KM.   +6 more
europepmc   +1 more source

Interfacial Bioengineering of Dynamic Networks Hybrid Hydrogel for Programmed Intervention in Oral Precancerous Epithelial States

Advanced Healthcare Materials, EarlyView.
This study develops a dual‐bioinspired hydrogel, MSA@PGel (macrophage membrane‐coated and salvianolic acid B/5‐aminolevulinic acid co‐loaded liposomes embedded in a polydopamine‐based gel), that integrates macrophage membrane‐mediated active targeting and mussel‐inspired wet adhesion for programmed intervention in oral precancerous lesions.
Xiaoxian Zhao, Ao Zheng, Zhengyan Zhao, Qilin Li, Tianhao Wan, Tanjun Deng, Ying Zhang, Lingyan Cao, Lan Wu   +8 more
wiley   +1 more source

l‑Proline-Carboxylic Acid-Based Hydrophobic Deep Eutectic Solvents: Thermophysical Properties and DFT Structural Insights. [PDF]

ACS Omega
Maharana S, Maharana RR, Samanta K, Mishra S.   +3 more
europepmc   +1 more source

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Chemical Speciation and Coordination Behavior of 8‑Hydroxyquinoline-2-carboxylic Acid with Divalent Cations in Aqueous Solution: An Irving-Williams Series Study. [PDF]

ACS Omega
Baryłka A, Bukrym R, Ryza I, Bretti C, Sinha S, Cappai R, Lando G, Akintola O, Plass W, Godlewska-Zyłkiewicz B, Brancato G, Milea D, Gama S.   +12 more
europepmc   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

Advanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu, Wentie Yang, Youzhi Hong, Yusen Qiao, Chaozhao Liang   +4 more
wiley   +1 more source

The rsmA mutant from Pseudomonas aeruginosa ID4365 is a non-virulent strain that is suitable for pyocyanin and phenazine-1-carboxylic acid production. [PDF]

PLoS One
Fabian Del-Olmo MJ, Montelongo-Martínez LF, Villafañe-Barajas GV, González-Valdez A, Flores-Vega VR, Rosales-Reyes R, Gudiño-Zayas ME, Rizo-Pica T, Tinoco-Valencia R, Escalante A, Soberón-Chávez G, Cocotl-Yañez M.   +11 more
europepmc   +1 more source

Oral Administration of the carboxylic acid ester prodrug NHC SN_9 protects mice from lethal Orthopoxvirus challenge: Implications for the Treatment of Monkeypox [PDF]

Andrei Siniavin, Vladimir А. Gushchin, Natal'ya Shastina, E.S. Darnotuk, S. I. Luyksaar, Inna V. Dolzhikova, Anna M. Inshakova, Nailya А. Zigangirova, Aleksandr Gintsburg, Denis Logunov   +9 more
openalex   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Bifunctional Iminophosphorane Superbases Enable the Highly Enantioselective Sulfa-Michael Addition to Fully Substituted Cyclopropene Carboxylic Acid Derivatives. [PDF]

J Am Chem Soc
Yuan K, Ristache AI, Kosc SM, Crumpton A, Dixon DJ.   +4 more
europepmc   +1 more source