SHORT-CHAIN CARBOXYLIC-ACIDS, A NEW CLASS OF TERATOGENS - STUDIES OF POTENTIAL BIOCHEMICAL-MECHANISMS [PDF]
Certain short-chain carboxylic acids (SCCA) appear to share a common teratogenic potential, although the structural requirements for activity remain obscure.
Coakley, ME +5 more
core +4 more sources
Cobalt-Catalyzed Tandem Deamination, Decarboxylation, and Dehomologation of Primary Amines to Carboxylic Acids in Water [PDF]
Selective transformation of carboxylic acids through oxidative deamination of primary amines is a catalytically challenging and useful transformation. Herein, we present a simple protocol for the transformation of primary amines to carboxylic acids with ...
Deep, Chowdhury, Arup, Mukherjee
core +2 more sources
Unexpected Isomerization of Oxetane-Carboxylic Acids [PDF]
[Image: see text] Many oxetane-carboxylic acids were found to be unstable. They easily isomerized into new (hetero)cyclic lactones while being stored at room temperature or slightly heated.
Rudenko, Tymofii V. +11 more
core +2 more sources
Visible Light-Induced Coupling of Carboxylic Acids with Alcohols and Amines [PDF]
The combination of activated carboxylic acids and alcohols or amines to access esters and amides, respectively, is a cornerstone of organic chemistry and has been well developed over the past century.
Karl, Scheidt +4 more
core +1 more source
Siloxy Esters as Traceless Activator of Carboxylic Acids: Boron-Catalyzed Chemoselective Asymmetric Aldol Reaction [PDF]
The catalytic asymmetric aldol reaction of carboxylic acids is among the most useful reactions for the synthesis of biologically active compounds and pharmaceuticals.
Taiki, Fujita +4 more
core +2 more sources
Facile, green, and functional group-tolerant reductions of carboxylic acids…in water [PDF]
Facile reductions of carboxylic acids to aldehydes or alcohols can be effected under mild conditions upon initial conversion to their corresponding S-2-pyridyl thioesters.
Bruce, Lipshutz +2 more
core +2 more sources
A carboxylic acid is an organic acid that contains a carboxyl group (C(=O)OH) attached to an R-group. The general formula of a carboxylic acid is R−COOH or R−CO2H, with R referring to the alkyl, alkenyl, aryl, or other group.
Małgorzata Wolniewicz
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Mechanochemical-Assisted Decarboxylative Sulfonylation of α,β-Unsaturated Carboxylic Acids with Sodium Sulfinate Salts [PDF]
Developing a green and efficient method for synthesizing vinyl sulfones is challenging and highly desirable. We hereby report a green, sustainable, and unprecedented mechanochemical-assisted approach for the decarboxylative sulfonylation of α,β ...
Barakha , Saxena +3 more
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Conversion of carboxylic acids to potassium acyltrifluoroborates (KATs) by Cu-catalyzed borylation of mixed anhydrides [PDF]
We report the preparation of potassium acyltrifluoroborates (KATs) from widely-available carboxylic acids. Mixed anhydrides of carboxylic acids were prepared using isobutyl chloroformate and transformed to the corresponding KATs using a commercial copper
Neal, Mankad +4 more
core +1 more source
Conversion of carboxylic acids to amides under the action of tantalum(V) chloride [PDF]
It was found that the reaction of aliphatic carboxylic acids with secondary amines under the action of tantalum (V) chloride leads to the selective formation of carboxamides.
Aliya, Amirova +5 more
core +1 more source

