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The Effects of Preoperative Serum Carcinoembryonic Antigen, Cancer Antigen 15-3 and Cancer Antigen 125 on the Prognosis of Breast Cancer Patients With Different Molecular Subtypes. [PDF]
Yilihamu Y+5 more
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Annals of Internal Medicine, 1986
The level of carcinoembryonic antigen (CEA) is often elevated in the serum of patients with cancer. This article reviews the clinical usefulness of this observation. Carcinoembryonic antigen is not useful for detecting asymptomatic cancer; its sensitivity and specificity are not high, particularly for early stages of disease, so in populations with low
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The level of carcinoembryonic antigen (CEA) is often elevated in the serum of patients with cancer. This article reviews the clinical usefulness of this observation. Carcinoembryonic antigen is not useful for detecting asymptomatic cancer; its sensitivity and specificity are not high, particularly for early stages of disease, so in populations with low
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Carcinoembryonic antigen in osteosarcoma
Journal of Surgical Oncology, 1977AbstractPlasma carcinoembryonic antigen (CEA) assay was done in 30 patients with osteosarcoma. CEA was found positive (> 2.5 ng/ml) in 17 of 21 patients who had active evidence of disease and negative (< 2.5 ng/ml) in all 9 patients who were in complete remission resulting from previous amputation or chemotherapy.
Gerald P. Murphy+5 more
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Studies on Carcinoembryonic Antigen
International Archives of Allergy and Immunology, 1972The presence of carcinoembryonic antigen (CEA) in saline extracts (SE) prepared from adenocarcinomas of the colon has been confirmed. This antigen was also detected in perchloric acid extracts (PAE) and in boiled and ethanol precipitated extracts (BE) of colonic tumors. CEA was present in BE preparations of feces from 4 of 8 patients with colon cancer.
F. Milgrom, C.J. Abeyounis
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Heterogeneity of the carcinoembryonic antigen
Immunochemistry, 1973Abstract Fractionation of carcinoembryonic antigen (CEA) by ECTEOLA-cellulose chromatography and by isoelectric focusing indicated that the antigen was heterogeneous. The fractions obtained were variable in their content of sialic acid, amino sugars, and amino acids.
John E. Coligan+7 more
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The antigenicity of carcinoembryonic antigen in man
International Journal of Cancer, 1975AbstractBinding of globulins to 125I CEA was detected in 10 of 24 sera from patients with cancer, 13 of 26 sera from blood donors, and 7 of 27 supernates of tumor‐cell suspensions. Binding was predominantly by IgM in 10 of 14 sera tested by radioimmunoelectrophoresis.
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Isolation and characterization for carcinoembryonic antigen
Immunochemistry, 1972Abstract Carcinoembryonic antigen (CEA) has been isolated from several tumors of the digestive tract. Comparisons of the products with one another and with CEA obtained from Dr. Gold have been made. CEA of two molecular sizes (6·8 S and 10·1 S) has been obtained, but the 6·8 S material is the one usually found.
Marianne L. Egan+3 more
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Carcinoembryonic Antigen Assay
Annals of Internal Medicine, 1978Excerpt To the editor: Discussions on the use of carcinoembryonic antigen (CEA) assay to detect malignant pleural effusion and malignant ascites (1, 2) would benefit from explicit summary of measur...
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Cystadenocarcinoma and carcinoembryonic antigen (CEA)
Cancer, 1978A 40-year-old woman with back pain, an abdominal and a serum CEA level of 200 ng/ml was found to have at laparotomy, a large but resectable mucinous retroperitoneal mass. Pathologic diagnosis revealed cystadenocarcinoma, probably of pancreatic origin. It is remarkable that the cyst fluid contained a CEA level 100,000-fold normal.
José P. Ferrer+3 more
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