Results 31 to 40 of about 1,057,278 (264)

Regulation of T cell expansion by antigen presentation dynamics [PDF]

open access: yesPNAS 2019, 116 (13) 5914-5919, 2018
An essential feature of the adaptive immune system is the proliferation of antigen-specific lymphocytes during an immune reaction to form a large pool of effector cells. This proliferation must be regulated to ensure an effective response to infection while avoiding immunopathology.
arxiv   +1 more source

Clinicopathological and Prognostic Significance of Cancer Antigen 15-3 and Carcinoembryonic Antigen in Breast Cancer: A Meta-Analysis including 12,993 Patients

open access: yesDisease Markers, 2018
Purpose The prognostic role of serum cancer antigen 15-3 (CA15-3) and carcinoembryonic antigen (CEA) in breast cancer remains controversial. In this study, we conducted a meta-analysis to investigate the prognostic value of these two markers in breast ...
Xuan Li   +5 more
semanticscholar   +1 more source

Electrochemical Immunosensor Using Electroactive Carbon Nanohorns for Signal Amplification for the Rapid Detection of Carcinoembryonic Antigen

open access: yesBiosensors, 2022
In this work, a novel sandwich-type electrochemical immunosensor was developed for the quantitative detection of the carcinoembryonic antigen, an important tumor marker in clinical tests.
Angélica Domínguez-Aragón   +4 more
doaj   +1 more source

Towards understanding the mechanisms of actions of carcinoembryonic antigen‐related cell adhesion molecule 6 in cancer progression

open access: yesCancer Science, 2018
Human carcinoembryonic antigen (CEA) is the prototypic member of a family of highly related cell surface glycoproteins that includes carcinoembryonic antigen‐related cell adhesion molecule 6 (CEACAM6) and others.
Balsam Rizeq, Z. Zakaria, A. Ouhtit
semanticscholar   +1 more source

Molecular tug of war reveals adaptive potential of an immune cell repertoire [PDF]

open access: yesarXiv, 2022
The adaptive immune system constantly remodels its lymphocyte repertoire for better protection against future pathogens. Its ability to improve antigen recognition on the fly relies on somatic mutation and selective expansion of B lymphocytes expressing high-affinity antigen receptors.
arxiv  

The effects of symmetry on the dynamics of antigenic variation [PDF]

open access: yesJ. Math. Biol. 66, 115-137 (2013), 2012
In the studies of dynamics of pathogens and their interactions with a host immune system, an important role is played by the structure of antigenic variants associated with a pathogen. Using the example of a model of antigenic variation in malaria, we show how many of the observed dynamical regimes can be explained in terms of the symmetry of ...
arxiv   +1 more source

HbA1c showed a positive association with carcinoembryonic antigen (CEA) level in only diabetes, not prediabetic or normal individuals

open access: yesJournal of clinical laboratory analysis (Print), 2019
This study was conducted to investigate the association of carcinoembryonic antigen (CEA) and glycated hemoglobin (HbA1c) in normal, prediabetic, and diabetic subjects.
Soie Chung, Yunhwan Lee, E. Roh
semanticscholar   +1 more source

Characteristics of carcinoembryonic antigen-producing colorectal cancers: A population based study [PDF]

open access: yesArchive of Oncology, 2019
Objectives: Serum carcinoembryonic antigen is a tumor marker often found to be elevated in colorectal cancer patients. Elevated carcinoembryonic antigen has been strongly associated with poor prognosis.
Groover Sarah   +5 more
doaj  

Ultrasensitive immunosensor for detecting CEA based on double amplified signal of graphene loaded CoFe2O4/Ag nanoparticles

open access: yesMicro & Nano Letters, 2021
Using Ag‐CoFe2O4‐GO nanocomposite as biosensor interface, a novel unlabelled electrochemical immunosensor was designed to detect tumour marker carcinoembryonic antigen. Here, Ag‐CoFe2O4‐GO was synthesized by one‐pot method as an immunological probe. They
Xiao Wang   +7 more
doaj   +1 more source

The role of tissue and serum carcinoembryonic antigen in stages I to III of colorectal cancer—A retrospective cohort study

open access: yesCancer Medicine, 2018
Tissue carcinoembryonic antigen (t‐CEA) and serum carcinoembryonic antigen (s‐CEA) expression profiles are the most useful tumor markers for the diagnosis and evaluation of colorectal cancer (CRC) worldwide; however, their roles in CRC progression remain
Guojun Tong   +7 more
semanticscholar   +1 more source

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