Results 121 to 130 of about 172,865 (359)

Machine Learning for Green Solvents: Assessment, Selection and Substitution

Advanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta, Janhavi Nistane, Abhishek Sose, Harikrishna Sahu, Rampi Ramprasad   +4 more
wiley   +1 more source

XPC Deficiency Activate Cisplatin‐Mediated Autophagy in Bladder Cancer by Limiting Novel PHRF1‐Mediated Ubiquitination of the p53 Protein

Advanced Science, EarlyView.
This study reveals that XPC regulates autophagy signaling beyond its noncanonical DNA repair role, uncovering the XPC‐p‐ATM‐KDM4A‐PHRF1 axis as a novel mechanism for autophagy modulation under DNA damage stress. It identifies PHRF1 as a novel p53 ubiquitin ligase.
Baixiong Zhao, Yaqin Huang, Jiazhong Shi, Xiaozhou Zhou, Johan Bourghardt Fagman, Liwei Wang, Sha Liu, Wuxing Wang, Yuting Liu, Zhiwen Chen, Jin Yang   +10 more
wiley   +1 more source

Occupational exposures of firefighting and prostate cancer risk in the Norwegian Fire Departments Cohort

Scandinavian Journal of Work, Environment & Health
OBJECTIVES: Excess incidence of prostate cancer (PC) is frequently observed among firefighters; however, the association with specific occupational exposures of firefighting, as well as the influence of a medical surveillance bias, remains unclear.
Niki Marjerrison, Tom K Grimsrud, Johnni Hansen, Jan Ivar Martinsen, Karl-Christian Nordby, Raymond Olsen, Jo S Stenehjem, Marit B Veierød, Kristina Kjærheim   +8 more
doaj   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source

Enhanced‐Type Quantitative Luminescence Recognition for Per‐ and Polyfluoroalkyl Substances (PFAS) by a Metal–Organic Framework Single Crystal

Angewandte Chemie, EarlyView.
A millimeter‐sized luminescent metal–organic framework (MOF) single crystal is developed as a robust, reusable sensor for per‐ and polyfluoroalkyl substances (PFAS). Unlike conventional sensing conducted by MOF powders, the single crystal enables easy usage, improved stability, and enhanced luminescence response, facilitating practical PFAS detection ...
Zongsu Han, Yifan Guo, Kun‐Yu Wang, Wenxuan Li, Jiatong Huo, Qingya Huang, Vladimir I. Bakhmutov, Yihao Yang, Rong‐Ran Liang, Peter R. Taylor, Wei Shi, Hong‐Cai Zhou   +11 more
wiley   +2 more sources

Media Coverage of EPA\u27s Draft Dioxin Reassessment Report [PDF]

, 1999
Using content analysis, the authors examine the utility of news media in democratic decision ...
Egolf, Brenda P., Fitzpatrick, Megan A., Friedman, Sharon M.   +2 more
core   +1 more source

Hierarchically Porous Nitrogen‐Doped Carbon with High Conductivity for Rapid and Efficient Cr(VI) Reduction

Advanced Science, EarlyView.
The d‐PNC(1100, 10%) catalyst, synthesized via a zinc‐based ionic liquid self‐sacrificing pore‐forming strategy to create a defect‐rich, hierarchical, nitrogen‐doped porous structure, enhances conductivity, promotes rapid mass transfer and synergistic catalytic activity, driving efficient Cr(VI) reduction in OA solution to generate Cr(III)‐OA complexes.
Danyan Lin, Jie Yang, Fengfeng Chen, Xishi Tai, Zhongshan Chen, Xinrong Guo, Xiangke Wang, Wen Yao   +7 more
wiley   +1 more source

Nanozymes Integrated Biochips Toward Smart Detection System

Advanced Science, EarlyView.
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen, Wang Zheng, Zhihui Zhang, Shenping Yu, Xinxin Hang, Han Wu, Xiao‐Wei Xiang, Wei Mu, Yanli Jiao, Zaizai Dong, Lingqian Chang   +10 more
wiley   +1 more source

Synergetic Relay Between Atomic Hydrogen and Chlorine Radicals Enables Efficient Nitrate‐to‐Nitrogen Gas Conversion

Advanced Science, EarlyView.
Using photoelectrochemical (PEC) deep denitrification technology, a novel synergistic reduction‐oxidation process enables efficient conversion of nitrate (NO3−) to nitrogen (N2), while suppressing key intermediate ammonium (NH4+) and toxic nitrite (NO2−) accumulation.
Yongjie Wang, Ying Tao, Chi Zhang, Shan Hu, Yuxin Shi, Jixing Wang, Jiacheng Zhang, Chen Cheng, Ying Wang, Guisheng Li, Zichao Lian, Dieqing Zhang   +11 more
wiley   +1 more source