Results 121 to 130 of about 162,800 (361)

On the Relentless Pursuit of an Oral Insulin Delivery System: How Far is Too Far?

open access: yesAdvanced Therapeutics, EarlyView.
Injectable insulin preparations have far outpaced oral ones by virtue of adequate bioavailability and are driven by innovations, including insulin pumps, real‐time blood glucose monitoring, and artificial intelligence. In contrast, oral insulin delivery systems, including nanomedicines, continue to struggle and lag due to varied reasons.
Sourav Bhattacharjee
wiley   +1 more source

Assessment of Pollutant Spread from a Building Basement with three Ventilation Systems [PDF]

open access: yesEuroAcademy on Ventilation and Indoor Climate - CLIMACADEMY Course 7: Experimental Assessment of Indoor Environment Parameters, Pamporovo : Bulgaria (2009), 2010
Ventilation aims at providing a sufficient air renewal for ensuring a good indoor air quality (IAQ), yet building energy policies are leading to adapting various ventilation strategies minimising energy losses through air renewal. A recent IAQ evaluation campaign in French dwellings shows important pollution of living spaces by VOCs such as ...
arxiv  

Advances in Symbiotic Bioabsorbable Devices

open access: yesAdvanced Science, EarlyView.
This review focuses on recent advances in bioabsorbable devices. This review concludes innovation at the material, device, and system levels, the significant advances toward biomedical applications. This review discusses and highlights the challenges and trends in symbiotic bioresorbable electronics, and provides a new direction for the development of ...
Chang Zhu   +3 more
wiley   +1 more source

Dynamic DNA Processing: A Microcode Model of Cell Differentiation [PDF]

open access: yesarXiv, 2013
A general theoretical framework is put forth to organize and understand various observed phenomena and mathematical relationships in the field of molecular biology. By modeling each cell in eukaryotic organisms as a processor having a unique set of allowed states, represented by a specific DNA sequence, we demonstrate a method by which gene expression ...
arxiv  

The carcinogenic effect of human smegma: An experimental study.I. Preliminary report [PDF]

open access: bronze, 1956
H.R. Pratt-Thomas   +4 more
openalex   +1 more source

Redressing the Silent Interim: Precautionary Action & Short Term Tests in Toxicological Risk Assessment [PDF]

open access: yes, 2001
The author recommends that a stronger emphasis be placed on creating and implementing short-term tests that use iterative, conservative-based, tiered procedures in conjunction with a precautionary attitude during the interim phase of toxicological risk ...
Riley, Timothy
core   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

open access: yesAdvanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li   +3 more
wiley   +1 more source

Misleading nomenclature in the IARC Monographs Programme: a straightforward solution to improve accuracy and clarity [PDF]

open access: yesExploration of Medicine
The International Agency for Research on Cancer (IARC) Monographs Programme plays an important role in cancer prevention by identifying potential carcinogenic hazards. However, the terminology used in IARC’s classifications and Monographs can confuse the
Miguel López-Lázaro
doaj   +1 more source

Bayesian Model-Averaged Benchmark Dose Analysis Via Reparameterized Quantal-Response Models [PDF]

open access: yesarXiv, 2014
An important objective in biomedical risk assessment is estimation of minimum exposure levels that induce a pre-specified adverse response in a target population. The exposure/dose points in such settings are known as Benchmark Doses (BMDs). Recently, parametric Bayesian estimation for finding BMDs has become popular.
arxiv  

PROS1‐MERTK Axis Drives Tumor Microenvironment Crosstalk and Progression in Papillary Thyroid Microcarcinoma

open access: yesAdvanced Science, EarlyView.
Identifying biomarkers associated with PTC, particularly those related to PTMC progression, is crucial for precise risk stratification and treatment planning. This study utilized single‐cell RNA sequencing on 19 surgical tissue specimens, confirmed PROS1/MERTK axis as a critical component of the cellular microenvironment and a key regulatory mechanism ...
Wenqian Zhang   +11 more
wiley   +1 more source

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