Anti-carcinogenic soyabean Bowman–Birk inhibitors survive faecal fermentation in their active form and do not affect the microbiota composition in vitro [PDF]
M. Carmen Marín‐Manzano +4 more
openalex +1 more source
Recent Developments in the Field of Air‐Stable Nickel(0) Precatalysts for Cross‐Coupling Reactions
The development of bench‐stable Ni(0) sources aims to replace air‐sensitive [Ni(COD)2] (cod = cycloocta‐1,5‐diene) with easy‐to‐handle alternatives. Through a targeted ligand design, using electron‐deficient dienes, carbenes, and fluorophosphines, researchers have achieved air‐ and moisture‐tolerant complexes that show high catalytic activity in cross ...
Franziska Flecken, Schirin Hanf
wiley +1 more source
Cancer Chemopreventive Properties of Glutelin Hydrolysate from Riceberry Bran Residues Against the Early Stage of Liver and Colon Carcinogenesis Induced by Chemicals in Rats. [PDF]
Pharapirom A +6 more
europepmc +1 more source
Synthetic Routes to the Carcinogen IQ and Related 3H-Imidazo[4,5-f]quinolines. [PDF]
Erik Ronne +8 more
openalex +1 more source
Sustainability in Analytical Chemistry Illustrated by Pharmaceutical Nitrosamine Testing
ABSTRACT Following the valsartan scandal in 2018, the testing of drug substances and drug products for N‐nitrosamines has become a critical and mandatory quality control measure. The European Pharmacopoeia chapter 2.5.42 currently describes three analytical methods for this purpose: HPLC–MS/MS, GC–MS, and GC–MS/MS.
Felix Bredendiek +2 more
wiley +1 more source
Global, regional, and national burden and projections to 2050 of occupational carcinogen-attributable nasopharyngeal and laryngeal cancer: a comprehensive analysis from the GBD 2021 study. [PDF]
Zhang H, Xue R, Kong X, Zhao M, Jin Z.
europepmc +1 more source
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal +14 more
wiley +1 more source

