Results 181 to 190 of about 63,809 (265)

Microbiome—pancreatic cancer crosstalk: From tumor biology to therapeutic intervention

iMetaOmics, EarlyView.
The intratumoral microbiome acts as a critical regulator in pancreatic cancer progression and therapeutic resistance. This comprehensive review delineates the origins of pancreatic microbes, elucidates their multifaceted mechanisms in driving immune suppression, metabolic reprogramming, and stromal desmoplasia, and highlights the clinical potential of ...
Yuqin Xie, Jingyuan Ye, Sheng Wang, Maoyun Liu, Fengsheng Dai, Mingzhen Bai, Yi Wang, Athena Savoji, Yu Wang, Phillip B. Hylemon, Huiping Zhou, Hui Li, Dewei Li   +12 more
wiley   +1 more source

AB-Free Kava and Dihydromethysticin Inhibit Chronic Hexavalent Chromium Exposure-Induced Cell Malignant Transformation through Down-Regulating RNA Splicing Factor SNRPA1 Expression. [PDF]

Chem Res Toxicol
Li E, Bian T, Finkelberrg M, Liu Z, Bi Z, Carlson D, Xing C, Yang C, Wang Z.   +8 more
europepmc   +1 more source

Climate change amplifies global mycotoxin exposure: Emerging risks and sustainable solutions

iMetaOmics, EarlyView.
Climate change intensifies mycotoxin contamination through rising temperatures, elevated CO2, and altered precipitation. Global surveys reveal a high and widespread prevalence of major mycotoxins in staple cereals, with low‐income countries bearing the greatest burden.
Mengyao Xue, Zheng Qu, Tingting Jiang, Antonio F. Logrieco, Antonio Moretti, Ke Dong, Yanpo Yao, Qi Zhang, Peiwu Li   +8 more
wiley   +1 more source

Knowledge is not enough: Skin cancer prevention requires policy. [PDF]

J Eur Acad Dermatol Venereol
Martin LK, Guitera P.
europepmc   +1 more source

Environmental chemicals and the tumor immune microenvironment

iMeta, EarlyView.
Impact of representative environmental chemicals on tumor immune microenvironment (TIME). Representative environmental chemicals are ubiquitously distributed across air, soil, aquatic systems, and biota. These toxicants enter the human body via multiple exposure routes, including inhalation, dietary intake, and dermal absorption, subsequently ...
Tongtong Zhang, Yanxia Hu, Weiran Zhang, Yang Jin, Chaoyang Sun, Afshin Samali, Shunqing Xu, Xia Sheng   +7 more
wiley   +1 more source

European Code Against Cancer, 5th edition - occupational exposures and cancer. [PDF]

Mol Oncol
Jochems SHJ, Vilahur N, van Tongeren M, Albin M, Baldi I, Consonni D, Crowley Q, Fervers B, Greinert R, Hoek G, Röösli M, Zeeb H, Schüz J, Feliu A, D'Souza E, Ritchie D, Espina C, Kromhout H.   +17 more
europepmc   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Transmembrane BAX inhibitor motif containing 1 inhibition of lysosomal degradation of TGF-β receptor 1 suppresses cellular senescence and hepatocarcinogenesis. [PDF]

J Biol Chem
Zhou D, Yu W, Zheng Y, Hou X, Zhang K, Qian X, Duan L, Feng S, Xue M, Zhu X, Zhang H, Zhang L, Wei L, Liu W, Jiang J, Zhang L.   +15 more
europepmc   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Inline Oxygenation in Drip‐Irrigated Citrus: How Much Agrochemical Reduction Is Needed to Achieve Net Environmental Benefits?

Irrigation and Drainage, EarlyView.
ABSTRACT The agronomic benefits of oxygen‐enriched irrigation, such as improved root development, enhanced nutrient uptake, and reduced fertiliser and pesticide requirements, are well documented. However, incorporating oxygenation devices into fertigation systems increases energy demand and material use, thereby incurring additional environmental ...
Alberto Imbernón‐Mulero, Saker Ben Abdallah, Mohamed Zied Dhraief, Jose F. Maestre‐Valero, Belén Gallego‐Elvira   +4 more
wiley   +1 more source