UGT2B15 Acts as a Critical Detoxification Barrier Against Chemi-Cal-Induced Hepatotoxicity and Carcinogenesis via the Androgen Receptor Axis. [PDF]
Zhao Y +8 more
europepmc +1 more source
ABSTRACT Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome and is characterized by an accelerated adenoma‐carcinoma sequence, a relatively higher prevalence of flat and subtle CRC precursor lesions, and exceptionally high adenoma miss rates despite intensive colonoscopy surveillance.
Robert Hüneburg +3 more
wiley +1 more source
ABSTRACT All cases of invasive cervical cancer (ICC) and subsets of high‐grade cervical intraepithelial neoplasia grade 2 or 3 (CIN2/3) and adenocarcinoma in situ (AIS) in Norway are tested for 37 human papillomavirus (HPV) genotypes, within a mandatory national surveillance system.
Terese Bekkevold +13 more
wiley +1 more source
Is Exposure to Certain Endocrine-Disrupting Chemicals Associated with Increased Skin Cancer Risk? [PDF]
Betsi G +3 more
europepmc +1 more source
Lifestyle Factors Associated With Colorectal Adenomas: Results From a Vietnamese Case–Control Study
ABSTRACT Although colorectal cancer (CRC) is the fourth most common cancer in Vietnam, evidence on lifestyle factors associated with colorectal adenomas (CRA) remains limited. We conducted a case–control study to examine lifestyle factors associated with CRA.
Chi Thi‐Du Tran +6 more
wiley +1 more source
From association to attribution: translational challenges in carcinogen-informed radiogenomics for pancreatic cancer. [PDF]
Sun M, Zang D, Chen J.
europepmc +1 more source
Human Protein Biomarkers Outperform Bacterial Proteins in Colorectal Cancer Detection
ABSTRACT Colorectal cancer (CRC) generally develops from precancerous adenomatous lesions, including advanced adenomas (AA), through a sequence of carcinogenic molecular alterations. The composition of the gut microbiota and the fecal proteome is known to differ between individuals with AA and CRC compared to controls, providing opportunities for ...
Roza C. M. Opperman +12 more
wiley +1 more source
A signature-agnostic test for differences between tumor mutation spectra reveals carcinogen and ancestry effects. [PDF]
Hart SFM, Alcala N, Feder AF, Harris K.
europepmc +1 more source
Familial Cancers Associated With Cancers of the Breast, Prostate, Colorectum, and Lung in Sweden
ABSTRACT Available epidemiological evidence shows that many cancers share familial risks, and this is increasingly confirmed by data on shared pathogenic germline gene variants between cancers. We decided to harness the world's largest resource on familial cancer to assess discordant familial risks for female breast (BC), prostate (PC), colorectal (CRC)
Frantisek Zitricky +5 more
wiley +1 more source
Navigating luminal heterogeneity: etiology-based proteogenomic subtyping for targeted treatment strategies in breast cancer. [PDF]
Chang YH +39 more
europepmc +1 more source

