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Review of human health exposure assessment frameworks in the United States and development of a unified framework for exposure assessment practitioners [PDF]

open access: yesFrontiers in Public Health
The process of conducting a human health exposure assessment has been framed as a stepwise approach by multiple organizations and various authors. However, the recommended steps within these frameworks can vary depending on the organization or author ...
Melanie D. Nembhard   +5 more
doaj   +2 more sources

Description and evaluation of the Community Multiscale Air Quality (CMAQ) modeling system version 5.1 [PDF]

open access: yesGeoscientific Model Development, 2017
The Community Multiscale Air Quality (CMAQ) model is a comprehensive multipollutant air quality modeling system developed and maintained by the US Environmental Protection Agency's (EPA) Office of Research and Development (ORD).
K. W. Appel   +22 more
doaj   +1 more source

A transgenic mice model of retinopathy of cblG-type inherited disorder of one-carbon metabolism highlights epigenome-wide alterations related to cone photoreceptor cells development and retinal metabolism

open access: yesClinical Epigenetics, 2023
Background MTR gene encodes the cytoplasmic enzyme methionine synthase, which plays a pivotal role in the methionine cycle of one-carbon metabolism.
Karim Matmat   +14 more
doaj   +1 more source

A harmonized chemical monitoring database for support of exposure assessments

open access: yesScientific Data, 2022
Measurement(s) occurrence of chemicals in environmental and biological media Technology Type(s) mass spectrometry (curation of public data) Sample Characteristic - Organism Homo sapiens • aquatic invertebrates • aquatic vertebrates/mammals • birds • fish
Kristin K. Isaacs   +12 more
doaj   +1 more source

Birch-induced allergic rhinitis: Results of exposure during nasal allergen challenge, environmental chamber, and pollen season

open access: yesWorld Allergy Organization Journal, 2023
Background: Pollen variation can affect field study data quality. Nasal allergen challenge (NAC) is considered the gold standard for evaluating allergic rhinitis, while environmental exposure chambers (EECs) are mainly used in phase 2 drug development ...
Alina Gherasim, MD   +4 more
doaj   +1 more source

KiESEL – the children’s nutrition survey module in KiGGS Wave 2 [PDF]

open access: yesJournal of Health Monitoring, 2017
Representative food consumption data for children are collected in KiESEL, the German nutrition survey for children aged 6 months up to five years conducted by the German Federal Institute for Risk Assessment (BfR).
Nadine Golsong   +3 more
doaj   +1 more source

Adding four-dimensional data assimilation by analysis nudging to the Model for Prediction Across Scales – Atmosphere (version 4.0) [PDF]

open access: yesGeoscientific Model Development, 2018
The Model for Prediction Across Scales – Atmosphere (MPAS-A) has been modified to allow four-dimensional data assimilation (FDDA) by the nudging of temperature, humidity, and wind toward target values predefined on the MPAS-A computational mesh.
O. R. Bullock Jr.   +3 more
doaj   +1 more source

Impacts of different characterizations of large-scale background on simulated regional-scale ozone over the continental United States [PDF]

open access: yesAtmospheric Chemistry and Physics, 2018
This study analyzes simulated regional-scale ozone burdens both near the surface and aloft, estimates process contributions to these burdens, and calculates the sensitivity of the simulated regional-scale ozone burden to several key model inputs with ...
C. Hogrefe   +8 more
doaj   +1 more source

Birch allergen challenges in allergic conjunctivitis using standard conjunctival allergen challenge and environmental exposure chamber

open access: yesClinical and Translational Allergy, 2021
Background Environmental exposure chambers (EECs) have been used extensively to study allergic rhinoconjunctivitis. Few studies have been published using EECs in conjunctivitis only, and none have used conjunctival allergen challenge as a selection ...
Alina Gherasim   +4 more
doaj   +1 more source

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