Results 1 to 10 of about 2,536,783 (302)

Development of Design Data for Propulsion PMR-15 Composites [PDF]

open access: yes, 1985
The continuing development of PMR-15 composite materials and their associated design properties is pacing the implementation of this technology on commercial aircraft.
Mclaren, D., Postlewaite, J.
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Estimating the environmental burden of disease in children and adolescents in Germany: limitations and possible solutions

open access: yesFrontiers in Public Health
IntroductionChildren and adolescents play an exceptional role in our society especially when it comes to safeguarding their health and given their higher susceptibility to environmental risk factors and ongoing physical development.MethodWe used data ...
Myriam Tobollik   +3 more
doaj   +1 more source

Distribution, variability, and predictors of urinary bisphenol A levels in 50 North Carolina adults over a six-week monitoring period

open access: yesEnvironment International, 2018
Bisphenol A (BPA) is commonly manufactured to make polycarbonate plastics and epoxy resins for use in consumer products and packaged goods. BPA has been found in several different types of environmental media (e.g., food, dust, and air).
Marsha K. Morgan   +5 more
doaj   +1 more source

The Emerging Role of Ten-Eleven Translocation 1 in Epigenetic Responses to Environmental Exposures. [PDF]

open access: yes, 2020
Mounting evidence from epidemiological studies and animal models has linked exposures to environmental factors to changes in epigenetic markers, especially in DNA methylation.
Brown, Anthony P, Ji, Hong, Zhu, Tao
core  

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

open access: yesMolecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Preparation of montmorillonite/chitosan/γ-polyglutamic acid nanoparticles and evaluation of their adsorption and antibacterial performance

open access: yesScientific Reports
In this study, montmorillonite (MMT)/chitosan (CS)/γ-polyglutamic acid (γ-PGA) nanoparticles were synthesized using MMT, CS, and γ-PGA as the matrix materials, with amino silane as the crosslinking agent.
Zuolong Yu   +8 more
doaj   +1 more source

Environmental impact of atmospheric NH3 emissions under present and future conditions in the eastern United States

open access: yesGeophysical Research Letters, 2008
Recent regulations require large‐scale emission reductions of NOx and SO2 in the eastern United States. These emission changes will alter the partitioning of ammonia between the gas and particle phases.
R. W. Pinder   +2 more
doaj   +1 more source

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