Environmental exposures and development [PDF]
Summarize recent studies exploring the relationship between paternal and maternal environmental exposures to chemicals before, at the time of and after conception to adverse developmental outcomes including preterm birth, death, structural and functional abnormalities and growth restriction.Recent studies have demonstrated that human pregnancy and ...
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Epigenetics and environmental exposures [PDF]
It is becoming increasingly apparent that genetic factors are inadequate to fully explain many processes that shape development and disease. For example, monozygotic twin pairs, despite sharing identical DNA sequences, are often discordant for many traits and diseases, indicating that the same genotype can give rise to distinct phenotypes.
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A Synergistic Antiobesity Effect by a Combination of Capsinoids and Cold Temperature Through Promoting Beige Adipocyte Biogenesis. [PDF]
Beige adipocytes emerge postnatally within the white adipose tissue in response to certain environmental cues, such as chronic cold exposure. Because of its highly recruitable nature and relevance to adult humans, beige adipocytes have gained much ...
Bannai, Makoto +5 more
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Why environmental exposures? [PDF]
Concerns about environmental health are rising. Publics, scientists and policymakers have grown increasingly alarmed about adverse health effects arising from catastrophic accidents such as the Bho...
Kelly Joyce, Laura Senier
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Modeling stratospheric intrusion and trans-Pacific transport on tropospheric ozone using hemispheric CMAQ during April 2010 – Part 2: Examination of emission impacts based on the higher-order decoupled direct method [PDF]
The state-of-the-science Community Multiscale Air Quality (CMAQ) modeling system, which has recently been extended for hemispheric-scale modeling applications (referred to as H-CMAQ), is applied to study the trans-Pacific transport, a phenomenon ...
S. Itahashi +5 more
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Environmental contaminant exposure can pose significant risks to human health. Therefore, evaluating the impact of this exposure is of great importance; however, it is often difficult because both the molecular mechanism of disease and the mode of action
Iida, Midori, Takemoto, Kazuhiro
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Mortality in young adults following in utero and childhood exposure to arsenic in drinking water. [PDF]
BackgroundBeginning in 1958, the city of Antofagasta in northern Chile was exposed to high arsenic concentrations (870 µg/L) when it switched water sources. The exposure abruptly stopped in 1970 when an arsenic-removal plant commenced operations.
Ferreccio, Catterina +5 more
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Assessment of the effect of air pollution controls on trends in shortwave radiation over the United States from 1995 through 2010 from multiple observation networks [PDF]
Long-term data sets of all-sky and clear-sky downwelling shortwave (SW) radiation, cloud cover fraction, and aerosol optical depth (AOD) were analyzed together with surface concentrations from several networks (e.g., Surface Radiation Budget Network ...
C.-M. Gan +7 more
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Exposure Prioritization (Ex Priori): A Screening-Level High-Throughput Chemical Prioritization Tool
To estimate potential chemical risk, tools are needed to prioritize potential exposures for chemicals with minimal data. Consumer product exposures are a key pathway, and variability in consumer use patterns is an important factor. We designed Ex Priori,
Heidi F. Hubbard +6 more
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Environmental Exposure and Leptospirosis, Peru
Human infection by leptospires has highly variable clinical manifestations, which range from subclinical infection to fulminant disease. We conducted a population-based, cross-sectional seroepidemiologic study in Peru to determine potential relationships of environmental context to human exposure to Leptospira and disease associated with seroconversion.
Johnson, MAS +14 more
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